174292-59-2

Basic information

• Product Name: Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)- (9CI)
• Synonyms: Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)- (9CI);cis-Methyl 3-hydroxycyclopentanecarboxylate;(1R,3S)-3-Hydroxycyclopentane carboxylic acid methyl ester
• CAS NO: 174292-59-2
• Molecular Formula: C₇H₁₂O₃
• Molecular Weight: 144.16838
• Product Categories: CARBOXYLICESTER
• Mol File: 174292-59-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)- (9CI)(174292-59-2)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)- (9CI)(174292-59-2)

Safety Data

• Hazardous Substances Data: 174292-59-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)(9CI) is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block in the synthesis of complex molecules with potential therapeutic applications.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, Cyclopentanecarboxylic acid, 3-hydroxy-, methyl ester, (1R-cis)(9CI) is utilized as a key component in the synthesis of drugs targeting specific medical conditions. Its versatility in chemical reactions allows for the creation of a wide range of therapeutic agents, contributing to the advancement of medical treatments and healthcare solutions.

Upstream product

• 32811-75-9 methyl 3-oxocyclopentane-1-carboxylate 
• 67-56-1 methanol 
• 98-78-2 3-Oxo-cyclopentanecarboxylic acid 
• 132076-27-8 (R)-methyl 3-oxocyclopentanecarboxylate 
• 13012-38-9 (1R)-3-oxocyclopentane-1-carboxylic acid 

Relevant articles and documents

Synthesizing method of cis-3-hydroxy-cyclopentane carboxylate or cyclohexane carboxylate and derivative thereof

The invention discloses a synthesizing method of cis-3-hydroxy-cyclopentane carboxylate or cyclohexane carboxylate and a derivative thereof. The method includes: a compound III serving as the raw material and hydrogen are subjected to one-step ring-opening reaction in a solvent in the presence of alkali and a catalyst to prepare the cis-3-hydroxy-cyclopentane carboxylate or cyclohexane carboxylateand the derivative thereof. The method is simple and practicable, high in product yield and suitable for large-scale production.

ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF

The present invention relates to novel adenine based inhibitors of adenylyl cyclase of the formula: wherein X, L, R1, R2, R5 are those defined herein. Compounds of the present invention are useful to treat cardiovascular diseases. The present invention also relates to a method of preventing heart failure by administering an effective amount of compound according to the invention following vascular injury and reperfusion therapy.

Horse Liver Alcohol Dehydrogenase-catalyzed Enantioselective Reduction of Cyclic Ketones: The Effect of the Hydrophobic Side Chain of the Substrate on the Stereoselectivity of the Reaction

Horse liver alcohol dehydrogenase (HLADH)-catalyzed enantioselective reductions of alkyl 3-oxocyclopentanecarboxylates, endo-5-acyloxybicycloheptan-2-ones and exo-5-acyloxybicycloheptan-2-ones gave the corresponding homochiral alcohols and ketones and the interaction between the hydrophobic side chain of the substrate and the hydrophobic zone in the active site played an important role in the specificity of the reduction.The stereoselectivities of the reactions were interpreted on the basis of the cubic space section model and a new rule, which contributes to development of a specificity analysis on the basis of the model, is introduced.