174543-78-3 Usage
Uses
Used in Pharmaceutical Industry:
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential biological activity and pharmacological properties. The presence of the Cbz protecting group on the nitrogen atom of the piperidine ring allows for selective reactions and the formation of complex molecules with desired properties.
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is used as a building block in the creation of complex molecules for pharmaceutical applications. Its unique structure and functional groups enable the development of innovative drugs with improved efficacy, selectivity, and safety profiles.
In Medicinal Chemistry Research:
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is used as a valuable tool in medicinal chemistry research for the exploration of novel drug candidates and the optimization of existing compounds. Its versatile chemical properties and reactivity allow for the synthesis of diverse molecular structures with potential therapeutic applications.
In Drug Development:
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is used as a precursor in the development of new drugs, where its unique structure and functional groups can be further modified to enhance the pharmacological properties of the final product. Its role in drug development is crucial for the discovery of innovative therapeutic agents with improved efficacy and reduced side effects.
Overall, 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is a versatile and essential compound in the pharmaceutical industry, playing a significant role in the synthesis, development, and optimization of various drugs. Its unique properties and potential applications make it a promising candidate for further research and development in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 174543-78-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,4 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174543-78:
(8*1)+(7*7)+(6*4)+(5*5)+(4*4)+(3*3)+(2*7)+(1*8)=153
153 % 10 = 3
So 174543-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H19NO4/c1-15(13(17)18)8-5-9-16(11-15)14(19)20-10-12-6-3-2-4-7-12/h2-4,6-7H,5,8-11H2,1H3,(H,17,18)
174543-78-3Relevant articles and documents
PYRROLOPYRIDINES AS KINASE INHIBITORS
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, (2009/12/23)
Compounds of Formula (I) are useful for inhibition of CHKl and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
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Page/Page column 41, (2008/06/13)
The present invention relates to compounds that are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres
Taylor, G. Mark,Baker, Stewart J.,Gedney, Andrea,Pearson, David J.,Sibley, Graham E. M.
, p. 1297 - 1300 (2007/10/03)
The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.
