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Tetrahydro-4-methoxy-2H-pyran-4-ol, also known as TAS-103, is a pyran derivative with potential anti-cancer properties. It has been studied for its ability to inhibit the growth of cancer cells and has shown promising results in preclinical studies. TAS-103's unique structure and mechanism of action make it an attractive candidate for further development as a therapeutic agent. Research on TAS-103 continues to explore its potential for the treatment of cancer and other diseases.

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  • 175982-83-9 Structure
  • Basic information

    1. Product Name: Tetrahydro-4-methoxy-2H-
    2. Synonyms: Tetrahydro-4-methoxy-2H-;Tetrahydro-4-methoxy-2H-pyran-4-carboxylic acid methyl ester
    3. CAS NO:175982-83-9
    4. Molecular Formula: C8H14O4
    5. Molecular Weight: 174.19436
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 175982-83-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Tetrahydro-4-methoxy-2H-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Tetrahydro-4-methoxy-2H-(175982-83-9)
    11. EPA Substance Registry System: Tetrahydro-4-methoxy-2H-(175982-83-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 175982-83-9(Hazardous Substances Data)

175982-83-9 Usage

Uses

Used in Pharmaceutical Industry:
Tetrahydro-4-methoxy-2H-pyran-4-ol is used as a potential anti-cancer agent for its ability to inhibit the growth of cancer cells. It has demonstrated promising results in preclinical studies, making it a candidate for further development as a therapeutic agent.
Used in Cancer Research:
Tetrahydro-4-methoxy-2H-pyran-4-ol is used in cancer research to explore its potential for the treatment of various types of cancer. Its unique structure and mechanism of action provide a basis for investigating its efficacy and safety in treating cancer.
Used in Drug Development:
Tetrahydro-4-methoxy-2H-pyran-4-ol is used in drug development to create novel treatment options for cancer patients. Its potential as a therapeutic agent is being further explored through ongoing research to understand its full capabilities and potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 175982-83-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,9,8 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175982-83:
(8*1)+(7*7)+(6*5)+(5*9)+(4*8)+(3*2)+(2*8)+(1*3)=189
189 % 10 = 9
So 175982-83-9 is a valid CAS Registry Number.

175982-83-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 4-methoxytetrahydro-2H-pyran-4-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175982-83-9 SDS

175982-83-9Downstream Products

175982-83-9Relevant articles and documents

Inhibitors of leukotriene B4. Synthesis and SAR of new β-enaminoester open-chain analogues of Zeneca ZD2138

Bird,Olivier

, p. 515 - 520 (2007/10/03)

A series of methoxy tetrahydropyranyl β-enaminoester has been discovered as inhibitors of LTB4 production. These are unusual open chain analogues of Zeneca ZD2138, the highly potent orally active 5-LO inhibitor under development for the treatment of asthma and rheumatoid arthritis. In vitro, compound 1a inhibited LTB4 formation in human whole blood with an IC50 of 0.04 μM. In inflamed exudate in the rat 1a inhibited formation of LTB4 with an oral ED50 3h after dosing of 3.0 mg/kg.

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