177990-54-4

Basic information

• Product Name: 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE
• Synonyms: 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE;4-(hydroxymethyl)-4-[(2-methylphenyl)methyl]-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 177990-54-4
• Molecular Formula: C19H29NO3
• Molecular Weight: 319.44
• Mol File: 177990-54-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE(177990-54-4)
• EPA Substance Registry System: 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE(177990-54-4)

Safety Data

• Hazardous Substances Data: 177990-54-4(Hazardous Substances Data)

Usage

Piperidine derivative

It is a derivative of piperidine, which is a heterocyclic organic compound with a six-membered ring containing one nitrogen atom.

Benzyl group

The compound contains a benzyl group (a phenyl group attached to a methyl group), which is a common structural motif in many pharmaceuticals and biologically active compounds.

Hydroxymethyl group

It has a hydroxymethyl group (a methyl group with an additional hydroxyl group) in its structure, which can participate in various chemical reactions and interactions.

Tert-butyloxycarbonyl (BOC) protecting group

The BOC group is a protecting group used in organic synthesis to prevent unwanted reactions, such as nucleophilic substitution or acid-base reactions, from occurring at the protected carbon atom.

Potential pharmaceutical applications

Due to its piperidine derivative nature, 1-BOC-4-[(2-METHYLPHENYL)METHYL]-4-(HYDROXYMETHYL)-PIPERIDINE may have potential applications in pharmaceutical research and drug development, as piperidine derivatives are commonly found in medications and biologically active compounds.

Further research needed

The specific use and properties of this compound would depend on further research and investigation into its potential pharmacological and chemical properties, as well as its interactions with biological targets and other molecules.

Upstream product

• 177990-34-0 N-t-butoxycarbonyl-4-(2-methylbenzyl)-isonipecotic acid benzyl ester 
• 7732-18-5 water 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 1126-09-6 4-carbethoxypiperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 498-94-2 isonipecotic acid 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 177990-33-9 4-Benzyloxycarbonyl-1-tert-butoxycarbonylpiperidine 

Relevant articles and documents

Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine derivatives as acetylcholine-binding protein ligands

The homomeric α7 nicotinic receptor (α7 nAChR) is widely expressed in the human brain that could be activated to suppress neuroinflammation, oxidative stress and neuropathic pain. Consequently, a number of α7 nAChR agonists have entered clinical trials as

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras

Inhibitors of farnesyl-protein transferase

The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.