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178248-34-5

Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)

    Cas No: 178248-34-5

  • USD $ 1.9-2.9 / Gram

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  • 178248-34-5 Structure

  • Basic information

    1. Product Name: Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)
    2. Synonyms: Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)
    3. CAS NO:178248-34-5
    4. Molecular Formula: C7H10O3
    5. Molecular Weight: 142.1525
    6. EINECS: N/A
    7. Product Categories: CARBOXYLICESTER
    8. Mol File: 178248-34-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)(178248-34-5)
    11. EPA Substance Registry System: Oxiranecarboxylic acid, 3-cyclopropyl-, methyl ester, (2R,3R)- (9CI)(178248-34-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 178248-34-5(Hazardous Substances Data)

178248-34-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 178248-34-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,2,4 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 178248-34:
(8*1)+(7*7)+(6*8)+(5*2)+(4*4)+(3*8)+(2*3)+(1*4)=165
165 % 10 = 5
So 178248-34-5 is a valid CAS Registry Number.

178248-34-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2R,3R)-3-cyclopropyl-2,3-epoxypropionate

1.2 Other means of identification

Product number -
Other names (2R,3R)-3-Cyclopropyl-oxirane-2-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:178248-34-5 SDS

178248-34-5Relevant articles and documents

Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel

Yamaguchi, Tetsuo,Harada, Naoyuki,Ozaki, Kunihiko,Arakawa, Hiroaki,Oda, Kouji,Nakanishi, Noriyuki,Tsujihara, Kenji,Hashiyama, Tomiki

, p. 1639 - 1644 (2007/10/03)

A novel 3'-desphenyl-3'-cyclopropyl analogue of docetaxel was synthesized from 10-deacetyl-baccatin III. The cytotoxicity of the new taxoid was evaluated against several human tumor cell lines, and it had ca. 20 times stronger activity against human colon cancer cell lines (WiDr and Colon 320) than that of docetaxel. This taxoid was converted to its water-soluble prodrugs that have 2'-substituted amino acid derivatives with spacer. The prodrugs had good solubility in saline and showed more potent antitumor activity against B 16 melanoma in mice than that of docetaxel.

Baccatin derivatives and processes for preparing the same

-

, (2008/06/13)

A compound represented by the formula [I]: STR1 wherein R3 represents a lower alkanoyl group; R4 represents a substituted or unsubstituted benzoyl group; ring A represents a substituted or unsubstituted cyclopropane ring; X represent

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