- New trimethoxybenzamides and trimethoxyphenylureas derived from dimethylcarbazole as cytotoxic agents. Part i
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A convenient synthesis of novel functionalized 1,4-dimethylcarbazole derivatives containing 3,4,5-trimethoxybenzamido-ureido or N-(3,4,5- trimethoxyphenyl)ureido group starting from their corresponding indole derivatives is reported. Three derivatives pre
- Panno, Antonella,Sinicropi, Maria Stefania,Caruso, Anna,El-Kashef, Hussein,Lancelot, Jean-Charles,Aubert, Geneviève,Lesnard, Aurélien,Cresteil, Thierry,Rault, Sylvain
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p. E294-E302
(2014/11/08)
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- Microwave-assisted solid-acid-catalyzed friedel-crafts alkylation and electrophilic annulation of indoles using alcohols as alkylating agents
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Alcohols are considered environmentally benign alkylating agents since the only by-product generated in their reactions is water. Herein, we report a microwave-assisted Friedel-Crafts alkylation and electrophilic annulation of indoles using alcohols as al
- Kulkarni, Aditya,Quang, Phong,Toeroek, Bela
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experimental part
p. 4010 - 4014
(2010/04/02)
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- Solvent-free solid acid-catalyzed electrophilic annelations: A new green approach for the synthesis of substituted five-membered N-heterocycles
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An effective microwave-induced, solid acid-catalyzed, environmentally benign synthesis of substituted pyrroles, indoles and carbazoles under solvent-free conditions is described. The new synthetic methodology is based on the use of a considerably strong solid acid, K-10 montmorillonite. Both the cyclialkylation of amines and annelation of pyrroles and indoles have been completed within minutes and provided excellent (75-98%) yields with practically 100% selectivity.
- Abid, Mohammed,Spaeth, Andrew,Toeroek, Bela
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p. 2191 - 2196
(2007/10/03)
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