- Synthesis of Benzopyran-Fused Flavone Derivatives via Microwave-Assisted Intramolecular C-H Activation
-
A microwave-assisted intramolecular direct arylation method for the synthesis of benzopyran-fused flavone derivatives containing natural flavone backbones is described. Different polyalkoxy flavones were synthesized and functionalized with 2-bromobenzyl bromide. The resulting compounds were subjected to palladium-catalyzed intramolecular direct arylation reactions supported by microwave irradiation to produce fused tetracyclic flavones. In the case of the 7-substituted chrysin derivative, the regioselectivity of the coupling was also examined.
- Sipos, Zoltán,Kónya, Krisztina
-
supporting information
p. 1610 - 1620
(2018/03/21)
-
- Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs
-
Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.
- -
-
Page/Page column 71
(2017/07/01)
-
- Synthesis of novel flavonoid derivatives as potential HIV-integrase inhibitors
-
Eighteen novel flavonoid derivatives - substituted chalcones and flavones were synthesized and characterized by using NMR, IR, UV/Vis spectroscopy and elemental analysis. The target compounds were achieved by using a sequence of simple and effective reactions starting from phloroglucinol. The initial hydroxyl groups were protected by methylation and in the final flavones the 5-OH group was selectively demethylated by means of AlBr3. 5-methoxy flavones exhibit a strong fluorescence, which was quenched after the removal of the methyl group.
- Mateeva, Nelly N.,Kode, Rao N.,Redda, Kinfe K.
-
p. 1251 - 1258
(2007/10/03)
-
- Synthesis and Characterization of Ruthenium(II) Complexes of 5-Hydroxyflavones
-
Bis(dimethyl sulfoxide)bis(flavonato)ruthenium(II) complexes, RuL2(DMSO)2, were synthesized by the reaction of dichlorotetrakis(dimethyl sulfoxide)ruthenium(II) with the sodium salts of 5-hydroxyflavone, 5-hydroxy-4'-methoxyflavone, and 5-hydroxy-3',4',5'
- Silva, Artur M. S.,Cavaleiro, Jose A. S.,Tarrago, Georges,Marzin, Claude
-
-
- The Preparation of Flavones and their Derivatives. Part I. Flavones and 4-Thioflavones.
-
A series of polysubstituted flavones has been prepared with particular emphasis on 3',4',5',5,7-pentahydroxyflavone and its ether derivatives.The preparation of 4-thioflavones has been undertaken to provide intermediates for the preparation of 4-iminoflav
- Briggs, Malcolm T.,Duncan, Graham L. S.,Thornber, Craig W.
-
p. 2461 - 2487
(2007/10/02)
-