181647-50-7

Basic information

• Product Name: (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL
• Synonyms: (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL;(5-Bromo-2-pyridyl)-phenyl-methanol
• CAS NO: 181647-50-7
• Molecular Formula: C₁₂H₁₀BrNO
• Molecular Weight: 264.12
• Mol File: 181647-50-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL(181647-50-7)
• EPA Substance Registry System: (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL(181647-50-7)

Safety Data

• Hazardous Substances Data: 181647-50-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL is used as a key intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique structure allows for the creation of complex molecules with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL is utilized as a building block in the synthesis of agrochemicals, contributing to the development of effective and targeted pest control agents.
Used in Medicinal Chemistry:
(5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL serves as a valuable component in medicinal chemistry, where it can be employed to design and synthesize novel compounds with potential therapeutic applications.
Used in Organic Synthesis:
As a versatile organic compound, (5-BROMO-PYRIDIN-2-YL)-PHENYL-METHANOL is used as a starting material or building block in organic synthesis to create a wide range of more complex molecules for various applications, including the development of new materials, dyes, and other specialty chemicals.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 119-61-9 benzophenone 
• 100-52-7 benzaldehyde 

Downstream Products

• 1374992-34-3 (5-bromopyridin-2-yl)(phenyl)methyl 2.2,2-trichloroethanimidoate; 
• 1613186-56-3 6-bromo-3-phenyl-[1,2,3]triazolo[1,5-a]pyridine 
• 1613186-51-8 [(5-bromopyridin-2-yl)phenylmethylene]hydrazone 
• 206357-52-0 (5-bromopyridin-2-yl)(phenyl)methanone 
• 1227862-76-1 (5-(4-nitrophenyl)pyridin-2-yl)(phenyl)methanol 

Relevant articles and documents

Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles

Using the bimetallic combination sBu2Mg?2 LiOR (R=2-ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo-arenes and -heteroarenes under mild reaction conditions and provides bromo-substituted magnesiu

Preparation and reactions of pyridinyl tellurides

Tellurium-metal exchange reaction of n-butyl 2-pyridinyl telluride derivatives with n-butyllithium or dilithium dimethylcyanocuprate proceeded smoothly to give the corresponding 2-pyridinylmetal derivatives, which are important intermediates for functionalization of pyridines.

Selective monolithiation of 2,5-dibromopyridine with butyllithium

Selective monolithiation of 2,5-dibromopyridine at either the 2-position or the 5-position is reported. Solvent and concentration strongly influence the selectivity. Coordinating solvents and higher concentration favor the 5- position while non-coordinati

Preparation and reactions of 2-pyridyltellurium derivatives

Pyridyltellurium derivatives have been prepared from the reaction of halopyridines with lithium butanetellurolate and the tellurium-metal exchange of pyridyltellurium derivatives has been investigated using butyllithium and dilithium dimethylcyanocuprate.