(5-Bromopyridin-2-yl)(phenyl)methanol

Base Information

Chemical Name:(5-Bromopyridin-2-yl)(phenyl)methanol
CAS No.:181647-50-7
Molecular Formula:C12H10BrNO
Molecular Weight:264.121
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60442189
Nikkaji Number:J752.101D
Mol file:181647-50-7.mol

Synonyms:181647-50-7;(5-bromopyridin-2-yl)(phenyl)methanol;(5-Bromo-2-pyridyl)-phenyl-methanol;(5-bromopyridin-2-yl)-phenylmethanol;(5-Bromo-pyridin-2-yl)-phenyl-methanol;(5-Bromopyridin-2-yl)phenylmethanol;2-Pyridinemethanol, 5-bromo-alpha-phenyl-;SCHEMBL5514077;DTXSID60442189;RSSXJOWWDMIIAJ-UHFFFAOYSA-N;MFCD06797257;AKOS017344921;5-Bromo-alpha-phenylpyridine-2-methanol;FT-0769487

Suppliers and Price of (5-Bromopyridin-2-yl)(phenyl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (5-Bromopyridin-2-yl)(phenyl)methanol

Chemical Property:

PSA：33.12000
LogP:2.92580
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.99458
Heavy Atom Count:15
Complexity:194

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=NC=C(C=C2)Br)O

Technology Process of (5-Bromopyridin-2-yl)(phenyl)methanol

There total 4 articles about (5-Bromopyridin-2-yl)(phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 624-28-2
2,5-dibromopyridine

: 119-61-9
benzophenone

: 181647-50-7
5-bromo-2-[(phenyl)hydroxymethyl]pyridine

Guidance literature:: 2,5-dibromopyridine; With n-butyllithium; In hexane; toluene; at -78 ℃; for 2h;

benzophenone; In hexane; toluene; at -78 ℃; for 1h;
DOI:10.1016/S0040-4039(00)00664-X

Reference yield: 70.0%

: 100-52-7
benzaldehyde

: n-butyl 5-bromo-2-pyridinyl telluride

: 181647-50-7
5-bromo-2-[(phenyl)hydroxymethyl]pyridine

Guidance literature:: n-butyl 5-bromo-2-pyridinyl telluride; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h;

benzaldehyde; In tetrahydrofuran; hexane; at 20 ℃; for 20h;
DOI:10.1002/jhet.5570380228

Reference yield:

: 624-28-2
2,5-dibromopyridine

: 181647-50-7
5-bromo-2-[(phenyl)hydroxymethyl]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexane; tetrahydrofuran / 0.17 h / 20 °C

1.2: 55 percent / hexane; tetrahydrofuran / 24 h / 20 °C

2.1: n-BuLi / hexane; tetrahydrofuran / 0.08 h / -78 °C

2.2: 70 percent / hexane; tetrahydrofuran / 20 h / 20 °C

With n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1002/jhet.5570380228