18375-65-0

Basic information

• Product Name: N-hexadecyl-D-gluconamide
• Synonyms: N-hexadecyl-D-gluconamide;Einecs 242-258-9
• CAS NO: 18375-65-0
• Molecular Formula: C₂₂H₄₅NO₆
• Molecular Weight: 419.5958
• EINECS: 242-258-9
• Mol File: 18375-65-0.mol

Chemical Properties

• Boiling Point: 676°Cat760mmHg
• Flash Point: 362.6°C
• Appearance: /
• Density: 1.085g/cm³
• Vapor Pressure: 3.57E-21mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: N-hexadecyl-D-gluconamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-hexadecyl-D-gluconamide(18375-65-0)
• EPA Substance Registry System: N-hexadecyl-D-gluconamide(18375-65-0)

Safety Data

• Hazardous Substances Data: 18375-65-0(Hazardous Substances Data)

Usage

Uses

Used in Cosmetic and Personal Care Industry:
N-hexadecyl-D-gluconamide is used as an emollient and moisturizing agent for its ability to improve the skin's moisture retention. It is often used in products such as lotions, creams, shampoos, and body washes to provide a smooth and soft skin feel.
Used in Household and Industrial Products:
N-hexadecyl-D-gluconamide is used as a surfactant and cleansing agent in various household and industrial products.
Used in Skincare Products:
N-hexadecyl-D-gluconamide is used as an antimicrobial agent in skincare products that target acne and other skin issues.

InChI:InChI=1/C22H45NO6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-23-22(29)21(28)20(27)19(26)18(25)17-24/h18-21,24-28H,2-17H2,1H3,(H,23,29)/t18-,19-,20+,21-/m1/s1

Upstream product

• 143-27-1 hexadecylamine 
• 526-95-4 gluconic acid 
• 50-99-7 D-glucose 
• 90-80-2 D-Glucono-1,5-lactone 

Relevant articles and documents

Pseudo-ceramide compound, method for preparing the same and cosmetic composition comprising the same

Disclosed is a pseudoceramide compound which is represented by chemical formula 1 by introducing alkylamine and an acyl group to D-gluconic acid. In the chemical formula 1, A is gluconic acid or an aqueous gluconic acid solution, R_1 refers to a straight or branched alkyl group with 10-22 carbon atoms, and R_2 refers to a straight or branched alkyl group with 11-21 carbon atoms or a straight or branched alkenyl group with 11-21 carbon atoms. According to the present invention, the pseudoceramide compound exhibits effects of improving skin moisturizing functions and compatibility.COPYRIGHT KIPO 2018

Pseudo-ceramide compound, method for preparing the same and cosmetic composition comprising the same

A disclosed pseudo-ceramide compound is represented by the chemical formula 1 by introducing an alkylamine or an acyl group into D-gluconic acid, wherein A is an aqueous solution of gluconic acid or gluconic acid, R_1 is a linear or branched alkyl group having 10 to 22 carbon atoms and R_2 is a linear or branched alkyl group having from 11 to 21 carbon atoms or a straight or branched alkenyl group having from 11 to 21 carbon atoms. According to the present invention, provided are the pseudo-ceramide compound having an effect of improving compatibility and skin moisturizing power, and a cosmetic composition comprising the same.COPYRIGHT KIPO 2018

Direct amidation of aldoses and decarboxylative amidation of α-keto acids: An efficient conjugation method for unprotected carbohydrate molecules

With use of iodine as an appropriate oxidant, unprotected and unmodified aldoses undergo oxidative amidation with a variety of functionalized amines, a-amino esters, and peptides, whereas KDO, sialic acid, and other a-keto acids proceed with oxidative dec

Biospecific emulsions

Oil-in-water emulsions can be formed using surfactants with biospecific headgroups. Emulsion droplets adhere to surfaces of microorganisms or to various biological surface bearing appropriate adhesins, thus delivering surfactant materials directly to various surfaces. Lipophilic materials and essential oils can be targeted in this way. The emulsions may be incorporated into oral hygiene non-food compositions or compositions for topical application to skin, hair or nails.