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ditazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 18471-20-0 Structure
  • Basic information

    1. Product Name: ditazole
    2. Synonyms: ditazole;ditazol;2,2'-[(4,5-Diphenyl-2-oxazolyl)imino]bisethanol;Agerophas;Apt-574;Diethamphenazole;S-222
    3. CAS NO:18471-20-0
    4. Molecular Formula: C19H20N2O3
    5. Molecular Weight: 324.378
    6. EINECS: 242-353-5
    7. Product Categories: N/A
    8. Mol File: 18471-20-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 505.5°Cat760mmHg
    3. Flash Point: 259.5°C
    4. Appearance: /
    5. Density: 1.237g/cm3
    6. Vapor Pressure: 4.83E-11mmHg at 25°C
    7. Refractive Index: 1.623
    8. Storage Temp.: Refrigerator
    9. Solubility: Chloroform (Slightly), Methanol (Slightly)
    10. CAS DataBase Reference: ditazole(CAS DataBase Reference)
    11. NIST Chemistry Reference: ditazole(18471-20-0)
    12. EPA Substance Registry System: ditazole(18471-20-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 18471-20-0(Hazardous Substances Data)

18471-20-0 Usage

Originator

Ageroplas,Serona,Italy,1973

Uses

Ditazole is a weak anti-inflammatory drug and a novel inhibitor of platelet aggregation.

Manufacturing Process

A solution of 5.1 grams 2-chloro-4,5-diphenyl-oxazole, 6.3 grams diethanolamine and 50 ml absolute ethanol was refluxed for 4 hours. The solvent was stripped at 1 mm and the oily residue was added at 60°C to 100 ml 50% ethanol; by cooling the hydro-alcoholic solution, 4.5 grams of 2-bis(β- hydroxyethyl)amino-4,5-diphenyl-oxazole was obtained (yield, 69.5%). The product crystallized from ethyl ether + petroleum ether, with a MP of 96 to 98°C.

Therapeutic Function

Antiinflammatory

Check Digit Verification of cas no

The CAS Registry Mumber 18471-20-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,7 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 18471-20:
(7*1)+(6*8)+(5*4)+(4*7)+(3*1)+(2*2)+(1*0)=110
110 % 10 = 0
So 18471-20-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18(24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2

18471-20-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(4,5-diphenyl-1,3-oxazol-2-yl)-(2-hydroxyethyl)amino]ethanol

1.2 Other means of identification

Product number -
Other names Ditazol [INN-Spanish]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18471-20-0 SDS

18471-20-0Downstream Products

18471-20-0Related news

PaperThe vascular protection of ditazole (cas 18471-20-0) and its effect on arachidonic acid metabolism09/03/2019

Ditazole (4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol) is a weak anti-inflammatory drug and has been shown to inhibit thrombus formation following electrically stimulated vascular damage in the microcirculation of the hamster cheek pouch. The drug was found to inhibit thromboxane A2 (TXA2) pr...detailed

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