1849-55-4Relevant articles and documents
Polymethylenedioxy bis(2-hydroxyiminomethylpyridinium) as in vitro reactivators of organophosphorous inhibited eel acetylcholinesterase
Demerseman, Pierre,Kiffer, Daniel,Debussche, Laurent,Lion, Claude,Royer, Rene,Sentenac-Roumanou, Henri
, p. 63 - 68 (1988)
The synthesis and in vitro AChE reactivating potency of 5 new bridged pyridinium-2 carbaldoximes are described.Tested as reactivators and protectors in vitro against 5 organophosphorous inhibitors, they show a particularly interesting activity against paraoxon and tabun.These oximes themselves are reversible AChE inhibitors.Keywords - acetylcholinesterase reactivators; organophosphorous poisons; bridged pyridinium oximes.
SPECTRAL STUDY OF 1,5-BIS(3-HYDROXY-2-PYRIDYLMETHYLIDENE) THIOCARBOHYDRAZONE
Romero, E. Sanchez,Ariza, J.L. Gomez,Perez, A. Guiraum
, p. 509 - 512 (1986)
The synthesis, spectral study and some of the physico-chemical properties of 1,5-bis(3-hydroxy-2-pyridylmethylidene) thiocarbohydrazone are described.The spectral characteristics of metallic ions-reagent are considered to establish the possible use of the compound as analytical photometric reagent.
Imparting hysteretic behavior to spin transition in neutral mononuclear complexes
Seredyuk, Maksym,Znovjyak, Kateryna,Mu?oz, M. Carmen,Galyametdinov, Yurii,Fritsky, Igor O.,Real, Jose A.
, p. 39627 - 39635 (2016/05/24)
A series of spin transition neutral compounds [FeL(NCS)2] has been synthesized and characterized by means of magnetic susceptibility studies, X-ray diffraction, IR and M?ssbauer spectroscopic, and calorimetric measurements (L = N,N-bis((3-alkox
Palladium(II) complexes of the thiosemicarbazone and N- ethylthiosemicarbazone of 3-hydroxypyridine-2-carbaldehyde: Synthesis, properties, and X-ray crystal structure
Demertzis, Mavroudis A.,Yadav, Paras Nath,Kovala-Demertzi, Dimitra
, p. 1959 - 1970 (2007/10/03)
Two novel, stable PdII complexes, compounds 3 and 4, of two 3-hydroxypyridine-2-carbaldehyde thiosemicarbazones, 1 and 2, resp., were prepared from Li2PdCl4. The single-crystal X-ray structure of complex 3 (=[Pd(2)Cl]) shows that the ligand monoanion coordinates in a planar conformation to the metal via the pyridyl N-, the imine N-, and the thiolato S-atoms. Intermolecular H-bonds, π-π, and CH...π interactions lead to a two-dimensional supramolecular assembly. The electronic, IR, UV/VIS, and NMR spectroscopic data of the two complexes are reported, together with their electrochemical properties. A sophisticated experimental procedure was used to determine the multiple dissociation constants of the ligands 1 and 2 by UV/VIS titration.
Design, synthesis, testing, and quantitative structure - Activity relationship analysis of substituted salicylaldehyde Schiff bases of 1-amino-3-hydroxyguanidine tosylate as new antiviral agents against coronavirus
Wang,Keck,Lien,Lai
, p. 608 - 614 (2007/10/02)
Further modifications of the structural features of Schiff bases of hydroxyaminoguanidines (SB-HAG) led to nine substituted salicylaldehyde Schiff bases of HAG (SSB-HAG) derivatives and three other SB-HAG derivatives. These new compounds were tested for t