14047-53-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(Hydroxymethyl)pyridin-3-ol is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the molecular structures of various drugs. Its presence in drug molecules can contribute to enhancing their therapeutic effects or modifying their pharmacokinetic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(Hydroxymethyl)pyridin-3-ol is utilized as an intermediate in the production of agrochemicals, potentially contributing to the development of new pesticides or other agricultural chemicals that can improve crop protection and yield.
Used in Organic Synthesis:
2-(Hydroxymethyl)pyridin-3-ol serves as a building block in the preparation of various heterocyclic compounds, which are important in organic synthesis for creating a wide range of chemical products with diverse applications.
Used in Medicine and Healthcare Research:
Due to its potential biological activities, 2-(Hydroxymethyl)pyridin-3-ol is being researched for its possible applications in medicine and healthcare. Its exploration in this field may lead to the discovery of new therapeutic agents or diagnostic tools.

InChI:InChI=1/C6H7NO2/c8-4-5-6(9)2-1-3-7-5/h1-3,8-9H,4H2

Upstream product

• 109-00-2 3-HYDROXYPYRIDINE 
• 50-00-0 formaldehyd 
• 67992-22-7 3-acetoxy-2-acetoxymethyl-pyridine 
• 80322-74-3 2-chloromethyl-3-hydroxypyridine hydrochloride 
• 3131-03-1 pristinamycin IA 

Downstream Products

• 83782-35-8 2-(4-Bromo-phenylsulfanylmethyl)-pyridin-3-ol 
• 1849-55-4 2-Formyl-3-hydroxypyridin 
• 556062-93-2 3-benzyloxy-2-benzyloxymethyl-6-iodopyridine 
• 556062-85-2 methyl 2,3,6-tri-O-benzyl-4-O-(5'-benzyloxy-6'-benzyloxymethyl-2'-pyridyl)-α-D-glucopyranoside 
• 556062-89-6 methyl 2,3,6-tri-O-benzyl-4-amino-4-deoxy-4-N-(5'-benzyloxy-6'-benzyloxymethyl-2'-pyridyl)-α-D-glucopyranoside 
• 1609986-26-6 (3-((4,5-dimethoxy-2-nitrobenzyl)oxy)pyridin-2-yl)methanol 
• 1609986-37-9 C₂₆H₂₀F₃N₃O₉ 
• 94454-57-6 3-(phenylmethoxy)-2-pyridinecarboxaldehyde 
• 139745-90-7 (E)-ethyl 3-(3-(benzyloxy)-2-pyridinyl)propenoate 
• 70381-91-8 2-(3-hydroxypropyl)pyridin-3-ol 
• 70381-92-9 2,3-dihydro-4H-pyrano<3,2-b>pyridine 
• 1438073-62-1 N-(3-chloro-4-fluorophenyl)-6-(3-(hexahydro-2H-pyrano[3,2-b]pyridin-5(3H)-yl)propoxy)-7-methoxyquinazolin-4-amine 
• 14173-30-9 3-hydroxy-2-hydroxymethylpyridine hydrochloride 

Relevant academic research and scientific papers

Synthesis and biological activity of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine

Methods for the synthesis of quaternary phosphonium salts based on 3-hydroxypyridine and 4-deoxypyridoxine were developed. Some of obtained compounds possess high antibacterial and antitumor activity in vitro.

ELECTROCHEMICAL REDUCTION OF PRISTINAMYCIN IA AND RELATED STREPTOGRAMINS IN AQUEOUS ACIDIC MEDIUM

The electrochemical reduction of the picolinoyl residue of pristinamycinIA and related streptogramins was performed at a mercury cathode, in aqueous medium.The presence of a peptidic lactone residue at the amide nitrogen atom markedly modified the expected cathodic behaviour of pyridyl carboxamides: in particular, we observed the reduction of the pyridyl ring into tetrahydropyridine derivatives.Thanks to a series of model heterocyclic carboxamides, increasing steric hindrance at the amide nitrogen position was shown to lead to enhanced reduction of the heterocyclic ring.

Acid-catalysed Rearrangement of 3-Acyl-6-alkoxy-5,6-dihydro-4H-1,2-oxazines: a Route to 3-Alkoxypyridine 1-Oxides

6-Alkoxy-5,6-dihydro-4H-1,2-oxazines (2) and (5) have been prepared by the reaction of chloro oximes (1) with enol ethers in the presence of sodium carbonate.The 3-phenyloxazine (2) rearranges to the nitrone (3) in methanolic HCl.In contrast, the 3-acyloxazines (5a-e) are converted into 3-alkoxypyridine 1-oxides (7) in aqueous alcoholic HCl.With HCl in acetic acid the oxazine (5a) is converted into 2-chloromethyl-3-hydroxypuridine hydrochloride (10a); analogous reactions take place with oxazines (5b) and (5d).Possible mechanisms for these reactions are discussed.

CERTAIN THIAZOLES AND OXAZOLES

The compounds are N,N'-substituted thioureas, ureas and guanidines which are H-2 histamine receptor inhibitors. Two compounds of this invention are N,N'-bis 2-((4-methyl-5-imidazolyl)methylthio) ethyl!thiourea and N,N'-bis 2-((4-methyl-5-imidazolyl)methylthio)ethyl!-N"-cyanoguanidine. "