186772-43-0

Basic information

• Product Name: Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodo-
• CAS NO: 186772-43-0
• Molecular Formula: C10H12BrI
• Molecular Weight: 339.014
• Mol File: 186772-43-0.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodo-(186772-43-0)
• EPA Substance Registry System: Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodo-(186772-43-0)

Safety Data

• Hazardous Substances Data: 186772-43-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois used as a reagent in organic synthesis for [application reason]. Its unique structure with bromo and iodo groups, along with the 1,1-dimethylethyl group, allows it to participate in a variety of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois used as a building block for the development of new drugs. Its specific functional groups can be further modified or used as starting materials for the synthesis of bioactive compounds with potential therapeutic applications.
Used in Chemical Research:
Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois also used as a research tool in chemical laboratories. It can be employed to study the reactivity and selectivity of various chemical reactions, as well as to explore new synthetic methodologies and reaction mechanisms.

Upstream product

• 129316-09-2 1,3-dibromo-5-t-butylbenzene 
• 769-92-6 4-tert-Butylaniline 
• 191983-33-2 2-bromo-4-tert-butyl-6-iodo-aniline 
• 91801-97-7 N-(2-bromo-4-tert-butylphenyl)acetamide 
• 20330-45-4 4-tert-butylacetanilide 
• 103273-01-4 2-bromo-4-tert-butylaniline 

Downstream Products

• 144001-06-9 1-(trimethylsilyl)-2-(3-bromo-5-tert-butylphenyl)acetylene 
• 863782-50-7 1-bromo-3-tert-butyl-5-[2-[tris(isopropyl)silyl]ethynyl]benzene 
• 863782-54-1 2-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-oxirane-2-carbaldehyde 
• 863782-52-9 2-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-prop-2-en-1-ol 
• 863782-53-0 (2-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-oxiranyl)-methanol 
• 863782-56-3 2-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-but-3-yn-2-ol 
• 863782-55-2 [3-tert-butyl-5-(2-ethynyl-oxiranyl)-phenylethynyl]-triisopropyl-silane 
• 863782-51-8 1-tert-butyl-3-[1-(tert-butyl-dimethyl-silanyloxymethyl)-vinyl]-5-[(triisopropylsilanyl)-ethynyl]-benzene 
• 863782-58-5 2,4-bis-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-but-3-yn-2-ol 
• 863782-59-6 acetic acid 1,3-bis-{3-tert-butyl-5-[(triisopropylsilanyl)-ethynyl]-phenyl}-1-methyl-prop-2-ynyl ester 
• 186772-49-6 C₂₈H₂₆ 
• 388092-70-4 C₄₆H₆₆Si₂ 
• 186772-55-4 C₅₆H₅₀ 
• 388092-72-6 C₇₄H₉₀Si₂ 

Relevant articles and documents

Design and Optimization of 3′-(Imidazo[1,2- a]pyrazin-3-yl)-[1,1′-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors

DDR1 is considered as a promising target for cancer therapy, and selective inhibitors against DDR1 over other kinases may be considered as promising therapeutic agents. Herein, we have identified a series of 3′-(imidazo[1,2-a]pyrazin-3-yl)-[1,1′-biphenyl]

ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND

An organometallic compound represented by Formula 1: wherein, in Formula 1, groups and variables are the same as described in the specification.

Synthesis of butadiyne-bridged [4n] metacyclophanes having exo-annular t-butyl groups

Butadiyne-bridged [44]- and [48]metacyclophanes having exo-annular t-butyl groups were prepared by intermolecular Eglinton coupling of the dimeric unit or by intramolecular ring closure of the linear tetramer. Comparison of the 1H and 13C NMR spectra of [44]metacyclophane with those of [48]cyclophane and diphenylbutadiyne revealed its prominent geometrical feature due to deformation of the triple bonds from linearity. The [44]Metacyclophane was converted into [08]thiophenometacyclophane in good yield by treatment with sodium sulfide.

Synthesis and self-association properties of diethynylbenzene macrocycles

We synthesized diethynylbenzene macrocycles (DBMs), cyclic oligomers of diethynylbenzene, having functional groups in the periphery of the macrocyclic framework and investigated their self-association properties in solution resulting from π-π stacking interaction. The tetrakis-DBM having hexadecyl ester groups showed dimerization behavior not only in chloroform-d, but also in o-dichlorobenzene-4.