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CAS

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188048-45-5

6-[2-(6-Hydroxyheptyl)thiazol-4-yl]-4,5-dimethoxypyridine-2-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 188048-45-5 Structure

  • Basic information

    1. Product Name: 6-[2-(6-Hydroxyheptyl)thiazol-4-yl]-4,5-dimethoxypyridine-2-carboxylic acid
    2. Synonyms: WS-75624B
    3. CAS NO:188048-45-5
    4. Molecular Formula: C18H24N2O5S
    5. Molecular Weight: 380.46638
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 188048-45-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-[2-(6-Hydroxyheptyl)thiazol-4-yl]-4,5-dimethoxypyridine-2-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-[2-(6-Hydroxyheptyl)thiazol-4-yl]-4,5-dimethoxypyridine-2-carboxylic acid(188048-45-5)
    11. EPA Substance Registry System: 6-[2-(6-Hydroxyheptyl)thiazol-4-yl]-4,5-dimethoxypyridine-2-carboxylic acid(188048-45-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 188048-45-5(Hazardous Substances Data)

188048-45-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 188048-45-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,0,4 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 188048-45:
(8*1)+(7*8)+(6*8)+(5*0)+(4*4)+(3*8)+(2*4)+(1*5)=165
165 % 10 = 5
So 188048-45-5 is a valid CAS Registry Number.

188048-45-5Downstream Products

188048-45-5Relevant articles and documents

Total synthesis of endothelin-converting enzyme antagonist WS75624 B

Huang, Sheng-Tung,Gordon, Dana M.

, p. 9335 - 9338 (1998)

A concise synthesis of endothelin-converting enzyme antagonist WS75624 B is reported. The natural product was prepared in seven steps from 2,4- dibromothiazole.

Synthesis of novel substituted pyridines as inhibitors of endothelin converting enzyme-1 (ECE-1)

Massa, Mark A.,Patt, William C.,Ahn, Kyunghye,Sisneros, Andre M.,Herman, Sarah B.,Doherty, Annette

, p. 2117 - 2122 (2007/10/03)

A series of bi-aryl pyridine carboxylic acids has been prepared and evaluated as inhibitors of ECE-1. The analogs were prepared by Pd catalyzed cross couplings of halogenated pyridines with heteroaryl organo -boranes, - tinate or -zincate derivatives.

The total synthesis of the natural product endothelin converting enzyme (ECE) inhibitor, WS75624 B

Patt, William C.,Massa, Mark A.

, p. 1297 - 1300 (2007/10/03)

The first total synthesis of WS75624 B, 1, an endothelin converting enzyme inhibitor produced in a fermentation broth of Saccharothrix sp. No. 75624 is reported herein. WS75624 B is synthesized in 14 steps from commercially available kojic acid, 2. The synthetic methodology allows for facile substitution at multiple sites on the molecule.

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