188923-75-3

Basic information

• Product Name: 4,6-Dibromo-3-hydroxy-2-methylpyridine
• Synonyms: 4,6-Dibromo-3-hydroxy-2-methylpyridine;4,6-dibroMo-2-Methylpyridin-3-ol
• CAS NO: 188923-75-3
• Molecular Formula: C₆H₅Br₂NO
• Molecular Weight: 266.92
• Mol File: 188923-75-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,6-Dibromo-3-hydroxy-2-methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dibromo-3-hydroxy-2-methylpyridine(188923-75-3)
• EPA Substance Registry System: 4,6-Dibromo-3-hydroxy-2-methylpyridine(188923-75-3)

Safety Data

• Hazardous Substances Data: 188923-75-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4,6-Dibromo-3-hydroxy-2-methylpyridine is used as a building block in the pharmaceutical industry for the creation of various compounds with potential therapeutic applications. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4,6-Dibromo-3-hydroxy-2-methylpyridine serves as a key intermediate for the synthesis of compounds with agricultural applications. Its reactivity enables the production of novel agrochemicals with enhanced pest control and crop protection properties.
Used as a Reagent in Chemical Research and Development:
4,6-Dibromo-3-hydroxy-2-methylpyridine is also utilized as a reagent in chemical research and development. Its unique properties make it suitable for various experimental applications, contributing to the advancement of scientific knowledge and the discovery of new chemical processes.
It is crucial to handle 4,6-Dibromo-3-hydroxy-2-methylpyridine with care, as it may possess hazardous properties. Its use should be confined to controlled environments to ensure safety and minimize potential risks.

Upstream product

• 1121-25-1 2-methyl-3-pyridinol 

Downstream Products

• 118399-86-3 2-bromo-5-hydroxyl-6-methylpyridine 
• 1346608-94-3 5-isopropoxy-6-methylpicolinic acid 
• 1392466-94-2 6-bromo-3-isopropoxy-2-methylpyridine 

Relevant articles and documents

1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS

Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.

TETRAZOLINONE COMPOUND AND USE THEREFOR

A tetrazolinone compound represented by formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, etc.; R3 represents a C1-C6 alkyl group, etc.; R4, R5, and R6 are the same or different and represent a hydrogen atom, etc.; A represents a C6-C10 aryl group optionally having one or more atoms or groups selected from Group P1, etc.; Q represents the following group Q1; and X represents an oxygen atom, has excellent control activity against pests.

Tetrazolinone compound, and use therefor

A tetrazolinone compound represented by formula (1) (in the formula, R1 and R2 are the same or different, and represent a hydrogen atom, or the like; R3 represents a C1-C6 alkyl group, or the like; R4, R5 and R6 are the same or different, and represent a hydrogen atom, or the like; A represents a C6-C10 aryl group, or the like, which may have one or more atoms or groups selected from group (P1); Q represents group (Q1), or the like; and X represents an oxygen atom, or the like). The tetrazolinone compound has an excellent pest-control effect.

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I) wherein R1a, R1b, R2, R3, (R4)n and ring (A) are as described in the description, to their preparation, to pharmaceutically acc

TRICYCLIC PIPERIDINE COMPOUNDS

The present invention relates to compounds of the formula (I), wherein R, R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), to methods for the preparation of such compounds of formula (I), and especially to their use as TPH modulators.

PYRAN-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to pyran spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the composition

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. The invention disclosed herein is also directed to a methods of preventing the onset of and/or recurrence of acute and chronic myeloid leukemia, as well as other cancers, comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist.

CHROMAN - SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to chroman spirocyclic piperidine amide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

PYRROLOPYRAZINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to pyrrolopyrazine-spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.