118399-86-3Relevant academic research and scientific papers
From a total synthesis of cepabactin and its 3:1 ferric complex to the isolation of a 1:1:1 mixed complex between iron (III), cepabactin and pyochelin
Klumpp, Cedric,Burger, Alain,Mislin, Gaetan L.,Abdallah, Mohamed A.
, p. 1721 - 1724 (2005)
A novel and straightforward total synthesis of cepabactin and its iron (III) complex is described. The latter compound was compared and identified to that obtained from the cultures of Burkholderia cepacia. On treatment of the growth medium of two different strains of B. cepacia with ferric chloride, we have isolated and characterized an unexpected mixed complex of iron (III), cepabactin and pyochelin.
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
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Paragraph 00197-00198, (2021/08/06)
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
TETRAZOLINONE COMPOUND AND USE THEREFOR
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Paragraph 0643; 0644, (2016/07/05)
A tetrazolinone compound represented by formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, etc.; R3 represents a C1-C6 alkyl group, etc.; R4, R5, and R6 are the same or different and represent a hydrogen atom, etc.; A represents a C6-C10 aryl group optionally having one or more atoms or groups selected from Group P1, etc.; Q represents the following group Q1; and X represents an oxygen atom, has excellent control activity against pests.
Tetrazolinone compound, and use therefor
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Paragraph 1019; 1020; 1021; 1022, (2016/10/08)
A tetrazolinone compound represented by formula (1) (in the formula, R1 and R2 are the same or different, and represent a hydrogen atom, or the like; R3 represents a C1-C6 alkyl group, or the like; R4, R5 and R6 are the same or different, and represent a hydrogen atom, or the like; A represents a C6-C10 aryl group, or the like, which may have one or more atoms or groups selected from group (P1); Q represents group (Q1), or the like; and X represents an oxygen atom, or the like). The tetrazolinone compound has an excellent pest-control effect.
TRICYCLIC PIPERIDINE COMPOUNDS
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Page/Page column 86, (2016/11/21)
The present invention relates to compounds of the formula (I) wherein R1a, R1b, R2, R3, (R4)n and ring (A) are as described in the description, to their preparation, to pharmaceutically acc
TRICYCLIC PIPERIDINE COMPOUNDS
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Page/Page column 144, (2015/06/08)
The present invention relates to compounds of the formula (I), wherein R, R1a, R1b, R2, R3, and X are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), to methods for the preparation of such compounds of formula (I), and especially to their use as TPH modulators.
PYRAN-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
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Paragraph 00261; 00262, (2013/07/31)
The invention relates to pyran spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the composition
CHROMAN - SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
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Page/Page column 153-154, (2012/09/10)
The invention relates to chroman spirocyclic piperidine amide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
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Page/Page column 139, (2012/10/07)
The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
PYRROLOPYRAZINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
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Paragraph 0338; 0339, (2013/03/26)
The invention relates to pyrrolopyrazine-spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
