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189442-43-1

4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine

    Cas No: 189442-43-1

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  • 189442-43-1 Structure

  • Basic information

    1. Product Name: 4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine
    2. Synonyms:
    3. CAS NO:189442-43-1
    4. Molecular Formula: C29H30F3N5
    5. Molecular Weight: 505.59115
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 189442-43-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine(189442-43-1)
    11. EPA Substance Registry System: 4-[1-Methyl-2-(4-piperidinyl)-4-[3-(trifluoromethyl)phenyl]-1H-imidazol-5-yl]-N-[1(S)-phenylethyl]pyridine-2-amine(189442-43-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 189442-43-1(Hazardous Substances Data)

189442-43-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 189442-43-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,4,4 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 189442-43:
(8*1)+(7*8)+(6*9)+(5*4)+(4*4)+(3*2)+(2*4)+(1*3)=171
171 % 10 = 1
So 189442-43-1 is a valid CAS Registry Number.

189442-43-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[3-methyl-2-piperidin-4-yl-5-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-N-[(1S)-1-phenylethyl]pyridin-2-amine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:189442-43-1 SDS

189442-43-1Downstream Products

189442-43-1Relevant articles and documents

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

Liverton, Nigel J.,Butcher, John W.,Claiborne, Christopher F.,Claremon, David A.,Libby, Brian E.,Nguyen, Kevin T.,Pitzenberger, Steven M.,Selnick, Harold G.,Smith, Garry R.,Tebben, Andrew,Vacca, Joseph P.,Varga, Sandor L.,Agarwal, Lily,Dancheck, Kim,Forsyth, Amy J.,Fletcher, Daniel S.,Frantz, Betsy,Hanlon, William A.,Harper, Coral F.,Hofsess, Scott J.,Kostura, Matthew,Lin, Jiunn,Luell, Sylvie,O'Neill, Edward A.,Orevillo, Chad J.,Pang, Margaret,Parsons, Janey,Rolando, Anna,Sahly, Yousif,Visco, Denise M.,O'Keefe, Stephen J.

, p. 2180 - 2190 (2007/10/03)

Novel potent and selective diarylimidazole inhibitors of p38 MAP (mitogen-activated protein) kinase are described which have activity in both cell-based assays of tumor necrosis factor-α (TNF-α) release and an animal model of rheumatoid arthritis. The SAR

An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)- amides

Claiborne, Christopher F.,Liverton, Nigel J.,Nguyen, Kevin T.

, p. 8939 - 8942 (2007/10/03)

N-(2-Oxo)-amides were efficiently converted to tri- and tetra- substituted imidazoles under neutral reaction conditions upon treatment with neat ammonium trifluoroacetate.

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