192330-66-8

Basic information

• Product Name: 1-(4-PHENOXYPHENYL)-1H-IMIDAZOLE
• Synonyms: 1-(4-PHENOXYPHENYL)-1H-IMIDAZOLE
• CAS NO: 192330-66-8
• Molecular Formula: C₁₅H₁₂N₂O
• Molecular Weight: 236.273
• Mol File: 192330-66-8.mol

Chemical Properties

• Melting Point: 97-99 °C
• Boiling Point: 387.9°C at 760 mmHg
• Flash Point: 188.4°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 7.12E-06mmHg at 25°C
• Refractive Index: 1.604
• Storage Temp.: 2-8°C
• PKA: 5.52±0.10(Predicted)
• CAS DataBase Reference: 1-(4-PHENOXYPHENYL)-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-PHENOXYPHENYL)-1H-IMIDAZOLE(192330-66-8)
• EPA Substance Registry System: 1-(4-PHENOXYPHENYL)-1H-IMIDAZOLE(192330-66-8)

Safety Data

• Hazardous Substances Data: 192330-66-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-Phenoxyphenyl)-1H-Imidazole is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows it to be a key component in the development of new medications, contributing to the advancement of healthcare and treatment options.
Used in Agrochemical Production:
In the agrochemical sector, 1-(4-Phenoxyphenyl)-1H-Imidazole serves as an intermediate in the production of various agrochemicals. Its application in this field aids in the development of effective solutions for agricultural challenges, such as pest control and crop protection.
Used in Organic Compound and Material Production:
This imidazole derivative is also utilized in the synthesis of other organic compounds and materials, broadening its applications across different industries. Its versatility in chemical reactions makes it a valuable asset in the creation of new materials with specific properties for various uses.
Used in Research and Development:
1-(4-Phenoxyphenyl)-1H-Imidazole holds potential biological and pharmacological properties that make it a subject of interest for researchers in medicine and biochemistry. Its possible applications in these fields are currently under investigation, with the aim of uncovering its full potential and contributing to scientific knowledge and innovation.

InChI:InChI=1/C15H12N2O/c1-2-4-14(5-3-1)18-15-8-6-13(7-9-15)17-11-10-16-12-17/h1-12H

Upstream product

• 288-32-4 1H-imidazole 
• 106-37-6 1.4-dibromobenzene 
• 108-95-2 phenol 
• 624-38-4 para-diiodobenzene 
• 106-39-8 bromochlorobenzene 
• 589-87-7 1,4-bromoiodobenzene 
• 637-87-6 1-Chloro-4-iodobenzene 
• 101-55-3 4-Bromodiphenyl ether 

Relevant articles and documents

Bis(NHC)-Pd-catalyzed one-pot competitive C-C*C-C, C-C*C-O, C-C*C-N, and C-O*C-N cross-coupling reactions on an aryl di-halide catalyzed by a homogenous basic ionic liquid (TAIm[OH]) under base-free, ligand-free, and solvent-free conditions

Bis(NHC)-Pd-catalyzed competitive asymmetrical C-C*C-C, C-C*C-O, C-C*C-N, and O-C*C-N cross-coupling reactions were performedviathe one-pot strategy in the presence of a new ionic liquid, which played the roles of solvent, base, and ligand simultaneously. The ionic liquid was prepared based on a methyl imidazolium moiety with hydroxyl counter anionsviaa Hofmann elimination on a 1,3,5-triazine framework (TAIm[OH]). Pd ions could be efficiently coordinated through the bis(NHC)-ligand moiety in the ionic liquid. Based on differences in the competitive kinetics of C-C cross-coupling reactions (Heck, Suzuki, and Sonogashira) with C-N and C-O cross-coupling reactions, and also differences in the kinetics of aryl halides, the coupling reactions could be selectively performed with a low amount of by-products. The competitive cross-coupling reactions were thus performed with high selectivity under mild reaction conditions.

C-N Cross-Couplings for Site-Selective Late-Stage Diversification via Aryl Sulfonium Salts

We report diverse C-N cross-coupling reactions of aryl thianthrenium salts that are formed site-selectively by direct C-H functionalization. The scope of N-nucleophiles ranges from primary and secondary alkyl and aryl amines to various N-containing hetero

Nitrogen-rich copolymeric microsheets supporting copper nanoparticles for catalyzing arylation of N-heterocycles

Nitrogen-rich copolymeric microsheets were synthesized through incomplete condensation of melamine and cyanuric chloride. The materials can be well-dispersed in polar solvent and perform excellently as supports or stabilizing agents for metal nanoparticles. The presence of nitrogen in the lattice improves their interaction with the copper nanoparticle precursor (Cu(II) ions). Monodispersed copper nanoparticles over these supports were obtained after reducing the absorbed precursors. The materials were characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). The catalytic C-N coupling reaction was selected as the model reaction to evaluate the catalytic performance of the supported nanoparticles. The catalysts show above 90% yield of coupling products and retain activity after a five-run recycling test. Surface chemistry and morphology transforming during the catalytic process was further investigated. Nitrogen-rich copolymeric microsheets were proven to be excellent supports and stabilizing agents for metal nanoparticles.