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7-Amino-heptan-1-ol, with the molecular formula C7H17NO, is an aliphatic amine and alcohol compound characterized by the presence of a primary amine group and a hydroxyl group. This colorless liquid exhibits a slight ammonia-like odor and is soluble in water. It is widely recognized for its role as an intermediate in the synthesis of pharmaceuticals and other organic compounds.

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  • 19243-04-0 Structure
  • Basic information

    1. Product Name: 7-AMINO-HEPTAN-1-OL
    2. Synonyms: 7-AMINO-HEPTAN-1-OL;7-AMINO-HEPTAN-1-OL, HYDROCHLORIDE;1-Heptanol, 7-aMino-
    3. CAS NO:19243-04-0
    4. Molecular Formula: C7H17NO
    5. Molecular Weight: 131.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 19243-04-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-AMINO-HEPTAN-1-OL(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-AMINO-HEPTAN-1-OL(19243-04-0)
    11. EPA Substance Registry System: 7-AMINO-HEPTAN-1-OL(19243-04-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 19243-04-0(Hazardous Substances Data)

19243-04-0 Usage

Uses

Used in Pharmaceutical Industry:
7-Amino-heptan-1-ol is utilized as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Organic Compounds Synthesis:
7-AMINO-HEPTAN-1-OL serves as a key intermediate in the synthesis of a range of organic compounds, facilitating the creation of diverse chemical products.
Used in Surfactant Production:
7-Amino-heptan-1-ol is employed as a raw material in the production of surfactants, which are essential in a variety of applications, including detergents, cleansers, and emulsifiers.
Used in Lubricant Manufacturing:
As a component in the manufacturing of lubricants, 7-Amino-heptan-1-ol helps in developing products that reduce friction and wear in various mechanical systems.
Used in Industrial Chemicals Production:
This versatile compound is also used as a raw material in the production of other industrial chemicals, highlighting its broad applicability across different sectors.
It is crucial to handle and store 7-Amino-heptan-1-ol with proper safety precautions and guidelines to ensure the well-being of individuals and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 19243-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,4 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19243-04:
(7*1)+(6*9)+(5*2)+(4*4)+(3*3)+(2*0)+(1*4)=100
100 % 10 = 0
So 19243-04-0 is a valid CAS Registry Number.

19243-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-aminoheptan-1-ol

1.2 Other means of identification

Product number -
Other names 1-Heptanol,7-amino

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19243-04-0 SDS

19243-04-0Relevant articles and documents

De-novo designed β-lysine derivatives can both augment and diminish the proliferation rates of E. coli through the action of Elongation Factor P

Connon, Stephen J.,Ghanim, Magda,Kelly, Vincent P.,McDonnell, Ciara M.,Mike Southern, J.

supporting information, (2022/01/24)

An investigation into the effect of modified β-lysines on the growth rates of eubacterial cells is reported. It is shown that the effects observed are due to the post translational modification of Elongation Factor P (EFP) with these compounds catalysed b

Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat

Barrett, Ryan R.G.,Nash, Claire,Diennet, Marine,Cotnoir-White, David,Doyle, Christopher,Mader, Sylvie,Thomson, Axel A.,Gleason, James L.

, (2021/12/01)

The combination of androgen receptor antagonists with histone deacetylase inhibitors (HDACi) has been shown to be more effective than antiandrogens alone in halting growth of prostate cancer cell lines. Here we have designed, synthesized and assessed a se

Ruthenium-Pincer-Catalyzed Hydrogenation of Lactams to Amino Alcohols

Chen, Jiangbo,Wang, Jiaquan,Tu, Tao

supporting information, p. 2559 - 2565 (2018/07/30)

By using the commercially available ruthenium pincer complex (Ru-MACHO-BH) as a catalyst, the challenging direct hydrogenation of lactams and analogues has been successfully accomplished to deliver corresponding value-added amino alcohols in good-to-excellent yields under mild reaction conditions. Remarkably, in addition to N-protected lactams, unprotected ones could also be readily reduced in the presence of a catalytic amount of weak base or even under neutral reaction conditions, which further highlights the broad substrate scope and the protocol efficiency.

A Novel Way To Radiolabel Human Butyrylcholinesterase for Positron Emission Tomography through Irreversible Transfer of the Radiolabeled Moiety

Sawatzky, Edgar,Al-Momani, Ehab,Kobayashi, Ryohei,Higuchi, Takahiro,Samnick, Samuel,Decker, Michael

, p. 1540 - 1550 (2016/08/28)

The enzyme butyrylcholinesterase (BChE) is known to be involved in the detoxification of xenobiotics in blood plasma and is associated with the progress of neurodegenerative disorders, diabetes type 2, obesity, and diseases of the cardiovascular system. In the present study, we developed carbamate-based inhibitors serving as positron emission tomography (PET) radiotracers with18F and11C as radioisotopes to visualize BChE distribution. These inhibitors are radiolabeled at the carbamate site and transfer this moiety onto BChE, which thus results in covalent and permanent radiolabeling of the enzyme. There are no comparable radiotracers for cholinesterases described to date. By ex vivo autoradiography experiments on mice brain slices and kinetic investigations, selective and covalent transfer of the radiolabeled carbamate moiety onto BChE was proven. These tracers might provide high resolution of BChE distribution in vivo to enable investigations into the pathophysiological mechanisms of diseases associated with alterations in BChE occurrence.

An acyl-SAM analog as an affinity ligand for identifying quorum sensing signal synthases

Kai, Kenji,Fujii, Hiroki,Ikenaka, Rui,Akagawa, Mitsugu,Hayashi, Hideo

supporting information, p. 8586 - 8589 (2014/07/22)

N-Acylhomoserine lactones (AHLs) are quorum sensing signals produced by Gram-negative bacteria. We here report the affinity purification of AHL synthases using beads conjugated with an enzyme inhibitor, which was designed based on the catalytic intermediate acyl-SAM. the Partner Organisations 2014.

SYNTHESIS AND USE OF DUAL TYROSYL-DNA PHOSPHODIESTERASE I (TDP1)- TOPOISOMERASE I (TOP1) INHIBITORS

-

Paragraph 0135, (2014/02/15)

The invention described herein pertains to the synthesis and use of certain N-substituted indenoisoquinoline compounds which inhibit the activity Tyrosyl-DNA Phosphodiesterase I (Tdp1) or Topoisomerase I (Top1) or both, or otherwise demonstrate anticancer activity. Also disclosed are novel N-substituted indenoisoquinoline compounds and pharmaceutical compositions comprising the novel N-substituted indenoisoquinoline compounds.

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

Demmer, Oliver,Frank, Andreas O.,Hagn, Franz,Schottelius, Margret,Marinelli, Luciana,Cosconati, Sandro,Brack-Werner, Ruth,Kremb, Stephan,Wester, Hans-Jürgen,Kessler, Horst

, p. 8110 - 8113 (2012/09/25)

There can be only one: Using a peptoid motif obtained by shifting the arginine side chain of a pentapeptide previously developed by Fujii et al. to the neighboring nitrogen atom restricts the conformational freedom and yields a conformationally homogeneou

Synthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase i (Tdp1)-topoisomerase i (Top1) inhibitors

Nguyen, Trung Xuan,Morrell, Andrew,Conda-Sheridan, Martin,Marchand, Christophe,Agama, Keli,Bermingam, Alun,Stephen, Andrew G.,Chergui, Adel,Naumova, Alena,Fisher, Robert,O'Keefe, Barry R.,Pommier, Yves,Cushman, Mark

experimental part, p. 4457 - 4478 (2012/08/07)

Substances with dual tyrosyl-DNA phosphodiesterase I-topoisomerase I inhibitory activity in one low molecular weight compound would constitute a unique class of anticancer agents that could potentially have significant advantages over drugs that work against the individual enzymes. The present study demonstrates the successful synthesis and evaluation of the first dual Top1-Tdp1 inhibitors, which are based on the indenoisoquinoline chemotype. One bis(indenoisoquinoline) had significant activity against human Tdp1 (IC 50 = 1.52 ± 0.05 μM), and it was also equipotent to camptothecin as a Top1 inhibitor. Significant insights into enzyme-drug interactions were gained via structure-activity relationship studies of the series. The present results also document the failure of the previously reported sulfonyl ester pharmacophore to confer Tdp1 inhibition in this indenoisoquinoline class of inhibitors even though it was demonstrated to work well for the steroid NSC 88915 (7). The current study will facilitate future efforts to optimize dual Top1-Tdp1 inhibitors.

A subtype-selective, use-dependent inhibitor of native AMPA receptors

Nilsen, Aaron,England, Pamela M.

, p. 4902 - 4903 (2008/02/03)

AMPA (α-amino-3-hydroxy-5-methyl-4-isooxazole) receptors (AMPARs) are glutamate-gated ion channels that play central roles in the mammalian brain, mediating fast excitatory synaptic transmission and underlying several forms of synaptic plasticity. Two sub

Matrix metalloprotease inhibitors

-

, (2008/06/13)

Compounds of formula (I): STR1 as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption disease, such as osteoporosis.

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