7-Amino-1-heptanol

Base Information

• Chemical Name: 7-Amino-1-heptanol
• CAS No.: 19243-04-0
• Molecular Formula: C7H17 N O
• Molecular Weight: 131.218
• Hs Code.: 2922199090
• DSSTox Substance ID: DTXSID70553270
• Nikkaji Number: J1.175.993I
• Wikidata: Q82433816
• Mol file: 19243-04-0.mol

Synonyms:7-AMINO-1-HEPTANOL;19243-04-0;7-aminoheptan-1-ol;1-Heptanol, 7-amino-;7-amino-heptan-1-ol;SCHEMBL63089;DTXSID70553270;KYJSXYQQYWMITG-UHFFFAOYSA-N;AMY18876;MFCD02094314;AKOS006276576;MS-21748;SY036829;CS-0088962;D74762;EN300-396356

Chemical Property of 7-Amino-1-heptanol

Chemical Property:

• PSA: 46.25000
• LogP: 1.58820
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 131.131014166
• Heavy Atom Count: 9
• Complexity: 48.2

Purity/Quality:

98%Min ^*data from raw suppliers

7-Amino-1-heptanol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCN)CCCO

Technology Process of 7-Amino-1-heptanol

There total 13 articles about 7-Amino-1-heptanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

7-aminoheptanoic acid (929-17-9) → 7-amino-1-heptanol (19243-04-0)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1016/j.bmcl.2022.128545

Reference yield: 80.0%

7-azido-heptan-1-ol (57395-45-6) → 7-amino-1-heptanol (19243-04-0)

Guidance literature:

With hydrogen; palladium; In methanol; at 20 ℃; for 16h; under 760.051 Torr;

DOI:10.1021/ja0705801

Reference yield:

7-bromoheptyl alcohol (10160-24-4) → 7-amino-1-heptanol (19243-04-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / NaN₃; n-Bu₄NBr / benzene / 16 h / Heating

2: 80 percent / H₂ / Pd / methanol / 16 h / 20 °C / 760.05 Torr

With sodium azide; tetrabutylammomium bromide; hydrogen; palladium; In methanol; benzene;

DOI:10.1021/ja0705801

upstream raw materials:

7-amino-heptanoic acid lactam

1,ω-diiodoheptane

(7-hydroxyheptyl)carbamic acid tert-butyl ester

7-azido-heptan-1-ol

Downstream raw materials:

4-Amino-salicylsaeure-(7-amino-heptylester)

{(S)-1-[(R)-1-(7-Hydroxy-heptylcarbamoyl)-1-methyl-2-phenyl-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

(E)-3-(3,4,5-Trimethoxy-phenyl)-acrylic acid 7-(7-hydroxy-heptylamino)-heptyl ester

N-[2-(4-benzyloxy-phenyl)-1-(7-hydroxy-heptylcarbamoyl)-ethyl]-butyramide