19352-10-4

Basic information

• Product Name: 2-methyl-2-phenyloxetane
• Synonyms: 2-methyl-2-phenyloxetane
• CAS NO: 19352-10-4
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148
• Product Categories: SF190085
• Mol File: 19352-10-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-methyl-2-phenyloxetane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-phenyloxetane(19352-10-4)
• EPA Substance Registry System: 2-methyl-2-phenyloxetane(19352-10-4)

Safety Data

• Hazardous Substances Data: 19352-10-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Methyl-2-phenyloxetane is used as a building block for the synthesis of various compounds in the pharmaceutical industry. Its unique structure and reactivity make it valuable for creating new drugs and medicinal agents, contributing to advancements in medicinal chemistry.
Used in Chemical Industry:
In the chemical industry, 2-Methyl-2-phenyloxetane is utilized as an intermediate in the synthesis of a range of organic compounds. Its role in creating new materials and its involvement in organic and polymer chemistry highlight its versatility and importance in chemical processes.
Due to its reactive properties, 2-Methyl-2-phenyloxetane should be handled with care to ensure safety in both research and industrial applications.

Upstream product

• 1774-47-6 trimethylsulfoxonium iodide 
• 98-86-2 acetophenone 
• 70775-39-2 dimethylsulfoxonium methylide 
• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 4436-23-1 2-phenyloxetane 
• 74-88-4 methyl iodide 
• 93938-04-6 S-methyl-S-morpholino-N-<(4-methylphenyl)sulfonyl>sulfoximine 
• 67-68-5 dimethyl sulfoxide 

Downstream Products

• 1402243-97-3 2-methyl-2-(2-methylphenyl)oxetane 
• 4525-48-8 N,N-dimethyl(2-methylbenzyl)amine 
• 1402243-99-5 2-methyl-2-(trimethylsilylphenyl)oxetane 
• 1402244-07-8 [2-(2-methyloxetan-2-yl)phenyl]diphenylmethanol 
• 1402244-31-8 C₁₁H₁₃⁽²⁾HO 
• 1402244-01-2 2-(2-bromophenyl)-2-methyloxetane 
• 1402244-02-3 2-(2-chlorophenyl)-2-methyloxetane 
• 1402244-12-5 ethyl 2'-(2-methyloxetane-2-yl)biphenyl-4-carboxylate 
• 1402244-13-6 2-(4'-methoxybiphenyl-2-yl)-2-methyloxetane 
• 1402244-14-7 2-[2-(2-methyloxetan-2-yl)phenyl]thiazole 
• 1402244-21-6 2-(2-chloro-6-methylphenyl)-2-methyloxetane 
• 1402244-20-5 C₁₀H₁₀⁽²⁾HClO 
• 1402244-23-8 C₁₁H₁₀⁽²⁾HF₃O 
• 1402244-22-7 C₁₁H₁₀⁽²⁾HF₃O 

Relevant articles and documents

Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols

The selective isomerization of strained heterocyclic compounds is an important tool in organic synthesis. An unprecedented regioselective isomerization of 2,2-disubstituted oxetanes into homoallylic alcohols is described. The use of tris(pentafluorophenyl

Flow microreactor synthesis of 2,2-disubstituted oxetanes via 2-phenyloxetan-2-yl lithium

A mild and sustainable synthesis of 2,2-disubstituted oxetanes has been achieved through the use of a fow microreactor system. By controlling the residence time a highly unstable intermediate such as 2-phenyloxetan-2-yl lithium can be generated and trappe

Flow microreactor synthesis of 2,2-disubstituted oxetanes via 2-phenyloxetan-2-yl lithium

A mild and sustainable synthesis of 2,2-disubstituted oxetanes has been achieved through the use of a flow microreactor system. By controlling the residence time a highly unstable intermediate such as 2-phenyloxetan-2-yl lithium can be generated and trapp

Exploiting the lithiation-directing ability of oxetane for the regioselective preparation of functionalized 2-aryloxetane scaffolds under mild conditions

Oxetane nudges in the DoM direction! Regioselective ortho-lithiation induced by an oxetane ring has been achieved. The reaction provides easy access to ortho-functionalized 2-aryloxetanes also through a lithiation/borylation Suzuki-Miyaura cross-coupling. The lithiation-directing ability of oxetane and the proton transfer mechanism have been investigated by competitive metalation and kinetic isotope effect studies. Copyright

2-Lithiated-2-phenyloxetane: A new attractive synthon for the preparation of oxetane derivatives

A valuable and direct method to access 2-substituted-2-phenyloxetanes by electrophilic quenching of the corresponding 2-lithiated derivative has, for the first time, been described. 2-Lithiated-2-phenyloxetane was found to be configurationally unstable. E

Reaction of sulfonimidamide Anions with Electrophiles

The reaction of alkylsulfonimidamides with bases gave corresponding carboanions, which were allowed to react with carbonyl compounds to give (2-hydroxyalkyl)sulfonimidamides in good yields.When benzoic anhydride or chlorotrimethylsilane was treated with these anions, corresponding phenacylsulfonimidamides or (trimethylsilyl)methylsulfonimidamides were obtained.On the other hand, the reaction of methyl N-p-tosylsulfonimidmorpholide anion with carbonyl compounds afforded epoxides or oxetanes in good yields.