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2-Chlorophenyl chloroformate, with the chemical formula C7H4Cl2O2, is a colorless to pale yellow liquid characterized by a pungent odor. It is a highly reactive chemical compound used primarily as a reagent in organic synthesis. Due to its corrosive and irritating properties, it requires careful handling to prevent harmful effects on the respiratory and nervous systems, especially since it is toxic if ingested or inhaled.

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  • 19358-41-9 Structure
  • Basic information

    1. Product Name: 2-CHLOROPHENYL CHLOROFORMATE
    2. Synonyms: 2-CHLOROPHENYL CHLOROFORMATE;ChloroforMic acid o-chlorophenyl ester;o-Chlorophenyl chloroforMate;2-chlorophenyl carbonochloridate
    3. CAS NO:19358-41-9
    4. Molecular Formula: C7H4Cl2O2
    5. Molecular Weight: 191.01
    6. EINECS: N/A
    7. Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks
    8. Mol File: 19358-41-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 221 °C(lit.)
    3. Flash Point: 230 °F
    4. Appearance: /
    5. Density: 1.37 g/mL at 25 °C(lit.)
    6. Vapor Pressure: 0.75 psi ( 20 °C)
    7. Refractive Index: n20/D 1.526(lit.)
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-CHLOROPHENYL CHLOROFORMATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-CHLOROPHENYL CHLOROFORMATE(19358-41-9)
    12. EPA Substance Registry System: 2-CHLOROPHENYL CHLOROFORMATE(19358-41-9)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 23/24/25-34
    3. Safety Statements: 23-26-36/37/39-45
    4. RIDADR: UN 3277 6.1/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 19358-41-9(Hazardous Substances Data)

19358-41-9 Usage

Uses

Used in Pharmaceutical Industry:
2-Chlorophenyl chloroformate is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its reactivity allows for the creation of a wide range of drug molecules, contributing to the development of new medications and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chlorophenyl chloroformate serves as an essential component in the production of pesticides and other crop protection agents. Its role in these applications helps to enhance crop yields and protect plants from harmful pests and diseases.
Used in Specialty Chemicals Production:
2-CHLOROPHENYL CHLOROFORMATE is also employed in the manufacturing of specialty chemicals, which are used in a variety of applications, including but not limited to, the production of dyes, polymers, and resins. Its versatility in chemical reactions makes it a valuable asset in this industry.
Used as a Chemical Intermediate in Dye, Polymer, and Resin Manufacturing:
2-Chlorophenyl chloroformate is used as a reactive intermediate in the synthesis of dyes, polymers, and resins. Its involvement in these processes is crucial for the development of new materials with specific properties required for various industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 19358-41-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,3,5 and 8 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 19358-41:
(7*1)+(6*9)+(5*3)+(4*5)+(3*8)+(2*4)+(1*1)=129
129 % 10 = 9
So 19358-41-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Cl2O2/c8-5-3-1-2-4-6(5)11-7(9)10/h1-4H

19358-41-9 Well-known Company Product Price

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  • Aldrich

  • (518441)  2-Chlorophenylchloroformate  97%

  • 19358-41-9

  • 518441-5G

  • 921.96CNY

  • Detail

19358-41-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-chlorophenyl) carbonochloridate

1.2 Other means of identification

Product number -
Other names 2-Chlorophenyl chloroformate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19358-41-9 SDS

19358-41-9Relevant articles and documents

An easy procedure for synthesis of 1,3,4-oxadiazines: A potential antimicrobial agents

Gurunanjappa, Pavithra,Kariyappa, Ajay Kumar

, p. 1687 - 1689 (2017)

An efficient and accessible procedure for the synthesis of 1,3,4-oxadiazines was developed. Reaction involves the cyclocondensation of phenylhydrazones catalyzed by a mild base triethylamine to produce 1,3,4-oxadiazines in good yields. The synthesized new

AZETIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF METABOLIC AND INFLAMMATORY DISEASES

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Page/Page column 55-56, (2012/08/07)

Compounds are disclosed that have a formula represented by the following: These compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example inflammatory conditions, infectious diseases, autoimmune diseases, diseases involving impairment of immune cell functions, cardiometabolic diseases, and/or proliferative diseases.

Preparation of chloroformates using bis(trichloromethyl)carbonate

Shi, Haibo,Hu, Weixiao,Sun, Yaquan

, p. 708 - 709 (2007/10/03)

The synthesis of eight chloroformates using bis(trichloromethyl) carbonate(BTC) is reported. It has been found that the yields by this BTC method are improved over the earlier phosgene method, and sodium hydroxide is better than pyridine as catalyst for the preparation of phenyl chloroformate.

Heat-sensitive recording materials and phenol compounds

-

, (2008/06/13)

Heat-sensitive recording materials contain an electron-donating chromogenic compound and an electron-attracting compound. The recording materials also contain at least one compound represented by the following formula: STR1 wherein R1 and R3 mean a hydrogen atom or an alkyl, aralkyl or aryl group, R2 and R4 denote an alkyl, alkenyl, aralkyl or aryl group, X1, X2, Y1 and Y2 stand for an oxygen or a sulfur atom, and --Z1 -- and --Z2 -- are a specific aromatic group. Also provided are phenol compounds represented by the following formula: STR2 wherein R1, R2, X1 and Y1 have the same meanings as defined above; R5 and R6 are a hydrogen or halogen atom or an alkyl, alkoxy, aralkyl, aryl or hydroxyl group; p and q stand for an integer of 1-4; R5 and R6 may be either the same or different when p and q represent an integer of 2 or greater; and --Z3 -- means a specific divalent group.

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