19434-36-7

Basic information

• Product Name: 2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE
• Synonyms: 2-(4-METHOXYPHENOXY)BENZALDEHYDE;2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE;2-(4-Methoxyphenoxy)benzaldehyde 97%
• CAS NO: 19434-36-7
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24
• Product Categories: Aldehydes;C10 to C21;Carbonyl Compounds
• Mol File: 19434-36-7.mol

Chemical Properties

• Melting Point: 57-61 °C
• Boiling Point: 138°C 0,01mm
• Flash Point: 151.9 °C
• Appearance: /
• Density: 1.166 g/cm³
• Vapor Pressure: 7.68E-05mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE(19434-36-7)
• EPA Substance Registry System: 2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE(19434-36-7)

Safety Data

• Hazard Codes: Xi,N
• Statements: 41-43-50
• Safety Statements: 26-36/37/39-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 19434-36-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-(4-Methoxyphenoxy)benzenecarbaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Dye and Pigment Production:
2-(4-METHOXYPHENOXY)BENZENECARBALDEHYDE serves as an intermediate in the production of dyes and pigments, enhancing the color properties and stability of these products.
Used in Polymer and Resin Synthesis:
2-(4-Methoxyphenoxy)benzenecarbaldehyde is utilized in the synthesis of polymers and resins, improving their structural and functional characteristics for various applications.
Used in Fragrance Industry:
As a fragrance ingredient, 2-(4-Methoxyphenoxy)benzenecarbaldehyde is used in perfumes and personal care products to provide unique and appealing scents.
It is important to handle and process 2-(4-Methoxyphenoxy)benzenecarbaldehyde with care due to its potential health and safety hazards, ensuring proper safety measures are in place during its use in various industries.

InChI:InChI=1/C14H12O3/c1-16-12-6-8-13(9-7-12)17-14-5-3-2-4-11(14)10-15/h2-10H,1H3

Upstream product

• 100-52-7 benzaldehyde 
• 150-76-5 4-methoxy-phenol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 89-98-5 2-chloro-benzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 5720-07-0 4-methoxyphenylboronic acid 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 1164549-12-5 C₁₆H₁₄O₄ 
• 1446253-25-3 (2E)-N-hydroxy-3-[2-(4-methoxyphenoxy)phenyl]-2-propenamide 
• 18733-07-8 (2-hydroxyphenyl)(4-methoxyphenyl)methanone 
• 1285506-31-1 C₁₈H₁₉N₃O₃ 
• 1285506-29-7 C₁₇H₁₆O₄ 
• 1285504-93-9 N-{(E)-3-[2-(4-hydroxy-phenoxy)-phenyl]-2-methyl-acryloyl}-guanidine 
• 1216945-76-4 C₂₁H₂₀O₄ 
• 1216944-11-4 C₂₀H₁₈O₃ 
• 1216944-86-3 C₂₁H₂₀O₄ 
• 1216947-52-2 C₁₈H₁₆O₃S 
• 1216955-43-9 C₂₈H₂₂O₃ 
• 1216946-29-0 C₂₄H₂₆O₃ 
• 1216945-29-7 C₂₁H₂₀O₄ 

Relevant articles and documents

Method for preparing aldehyde compounds by oxidative cleavage of carbon-carbon bonds of terminal alkene compounds

The invention discloses a method for preparing aldehyde compounds by oxidizing and breaking carbon-carbon bonds of terminal alkene compounds. The method comprises the following steps: adding an alkene-terminated compound, an additive and a nitrogen-doped mesoporous carbon-loaded monatomic catalyst into a fatty primary alcohol solvent, putting into a pressure container, sealing, introducing oxygen source gas with a certain pressure, controlling the pressure of the oxygen source gas to be 0.1-1MPa and the reaction temperature to be 80-150 DEG C, and obtaining a reaction product, namely the aldehyde compound. The nitrogen-doped mesoporous carbon-loaded monatomic catalyst adopted by the invention is high in activity, the highest separation yield of the aldehyde compound as a reaction product reaches 99%, the method is wide in application range, the reaction conditions are easy to control, the catalyst can be recycled, the post-treatment is simple, and the method is suitable for industrial production.

Mildness in preparative conditions directly affects the otherwise straightforward syntheses outcome of Schiff-base isoniazid derivatives: Aroylhydrazones and their solvolysis-related dihydrazones

Aroylhydrazones are versatile compounds with a series of applications, from biological to technological spheres. The simplicity of their preparation allows for a great chemical variability and synthetic manageability. However, the process can be not as st

Formation and Disproportionation of Xanthenols to Xanthenes and Xanthones and Their Use in Synthesis

A facile and versatile strategy employing TiCl4-mediated cyclization followed by a Cannizzaro reaction has been developed for the synthesis of various xanthene derivatives. The reaction proceeded smoothly to afford both xanthenes/xanthones or their sulfur derivatives and tolerated a wide range of electronically diverse substrates. Using this methodology, pranoprofen was synthesized in three steps in 59% overall yield from commercially available starting materials.

Identification of an Oxalamide Ligand for Copper-Catalyzed C?O Couplings from a Pharmaceutical Compound Library

A typical pharmaceutical compound library is stocked with molecular diversity and could provide a platform for the discovery of new ligand structures. Herein, we describe the use of this approach in combination with high throughput screening to identify N,N’-bis(thiophene-2-ylmethyl)oxalamide as a ligand that is generally effective for copper-catalyzed C?O cross-couplings to prepare both biarylethers as well as phenols under mild conditions.

In(OTf)3 catalyzed reductive etherification of 2-aryloxybenzaldehydes and 2-(arylthio)benzaldehydes

2-Aryloxybenzaldehydes and 2-(arylthio)benzaldehydes undergo reductive etherification in presence of 5 mol% In(OTf)3 and stoichiometric amount of Et3SiH under solvent free conditions to generate novel symmetrical dibenzyl ethers and thioethers in excellent yields. In(OTf)3 is found to be superior in terms of catalytic activity over the other metal triflates tested for the reaction. Xanthenes and thioxanthenes, as anticipated, could not be obtained under these conditions.

Pyrimidine onium compound and application thereof

The invention relates to a pyrimidine onium compound, nitride oxides, salt of the nitride oxides and a composition comprising the compound. The invention further relates to an application of the compound to plant pest control.

Nickel-catalyzed denitrative etherification of activated nitrobenzenes

Electron-deficient nitrobenzenes were coupled with phenols/alcohols to form diaryl/alkyl aryl ethers by the aid of NiCl2 as the catalyst. The reactions were conducted under ligand- and oxidant-free conditions without the exclusion of air or moisture. The initial studies upon the mechanism of the reaction revealed two solvent-dependent approaches. In molten TBAB, SNAr mechanism seems to be predominated, while, in DMF, the reaction might include the radical species.

Immobilized palladium nanoparticles on MNPs@A-N-AEB as an efficient catalyst for C-O bond formation in water as a green Solvent

Palladium nanoparticles immobilized on the magnetic nanoparticles@2-amino-N-(2-aminoethyl) benzamide (MNPs@A-N-AEB.Pd0) have been presented as an efficient, and reusable magnetically heterogeneous catalyst for the C-O coupling reaction, namely Ullmann condensation reactions in an aqueous medium. This heterogeneous catalyst shows superior reactivity for the C-O arylation of different aryl halide (chloride, bromide, and iodide) with phenol derivatives to afford the desired products in good to excellent yields within short reaction time. Moreover, the catalyst can be easily recovered and reused for seven runs without loss of catalytic activity. The catalyst was characterized by several techniques, such as FT-IR, SEM, TEM, EDS, XRD, TGA and ICP-OES.

Cross dehydrogenative coupling via base-promoted homolytic aromatic substitution (BHAS): Synthesis of fluorenones and xanthones

Cross dehydrogenative coupling reactions occurring via base-promoted homolytic aromatic substitutions (BHASs) are reported. Fluorenones and xanthones are readily prepared via CDC starting with readily available ortho-formyl biphenyls and ortho-formyl biphenylethers, respectively. The commercially available and cheap tBuOOH is used as an oxidant. Initiation of the radical chain reaction is best achieved with small amounts of FeCp2 (0.1 or 1 mol %).

Metal-free oxidative coupling: Xanthone formation via direct annulation of 2-aryloxybenzaldehyde using tetrabutylammonium bromide as a promoter in aqueous medium

A metal-free intramolecular annulation of 2-aryloxybenzaldehydes to xanthones is disclosed, which proceeds through the direct oxidative coupling of an aldehyde C-H bond and aromatic C-H bonds using tetrabutylammonium bromide (TBAB) as a promoter in aqueous medium. This strategy works smoothly in the presence of both electron-donating and electron-withdrawing groups, and displays good tolerance towards catalytically reactive substituents, thus promising further functionalizations of xanthone products.