19459-33-7

Basic information

• Product Name: 4-broMo-9H-fluorene
• Synonyms: 4-broMo-9H-fluorene;9H-Fluorene, 4-bromo-
• CAS NO: 19459-33-7
• Molecular Formula: C₁₃H₉Br
• Molecular Weight: 245.11456
• Mol File: 19459-33-7.mol

Chemical Properties

• Melting Point: 165 °C
• Boiling Point: 350.3°Cat760mmHg
• Flash Point: 166.8°C
• Appearance: /
• Density: 1.489g/cm³
• Vapor Pressure: 8.99E-05mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: 4-broMo-9H-fluorene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-broMo-9H-fluorene(19459-33-7)
• EPA Substance Registry System: 4-broMo-9H-fluorene(19459-33-7)

Safety Data

• Hazardous Substances Data: 19459-33-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4-bromo-9H-fluorene is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with enhanced properties.
Used in Agrochemical Production:
In the agrochemical industry, 4-bromo-9H-fluorene is utilized as a precursor in the production of pesticides and other agrochemicals, contributing to the development of more effective and safer products for agricultural use.
Used in Organic Chemistry Research:
4-bromo-9H-fluorene is employed as a building block in organic chemistry research for the synthesis of complex organic molecules, facilitating the discovery and creation of novel compounds with potential applications in various fields.
Used in the Development of New Materials and Technologies:
Due to its photophysical properties, 4-bromo-9H-fluorene is used in the development of new materials and technologies, such as in optoelectronics and photovoltaics, where its unique characteristics can be harnessed for innovative applications.
Used in Organic Synthesis as a Reagent:
4-bromo-9H-fluorene is used as a reagent in organic synthesis, providing a valuable tool for the construction of carbon-carbon and carbon-heteroatom bonds, which are essential in the formation of a wide range of organic compounds.

InChI:InChI=1/C13H9Br/c14-12-7-3-5-10-8-9-4-1-2-6-11(9)13(10)12/h1-7H,8H2

Upstream product

• 1528732-82-2 2-bromo-2'-(cyclohepta-2,4,6-trien-1-yl)-1,1'-biphenyl 
• 13029-09-9 2,2'-dibromobiphenyl 
• 500545-92-6 4-Ethoxycarbonylamino-fluoren 
• 7315-93-7 fluorene-4-carboxylic acid chloride 
• 86-73-7 9H-fluorene 
• 58775-05-6 2,7-di-tert-butyl-9H-fluorene 
• 91611-97-1 4-bromo-2,7-di(tert-butyl)-9H-fluorene 
• 99514-93-9 4-bromo-fluoren-9-ol 
• 7083-63-8 4-Aminofluorene 

Downstream Products

• 19462-79-4 4-bromophenanthrene 
• 19459-34-8 4-Brom-fluoren-9-carbonsaeure 
• 4269-17-4 4-bromo-9H-fluorene-9-one 

Relevant articles and documents

Preparation of high purity 4-bromofluorenone method of

The invention relates to a novel method for preparing high-purity 4-bromofluorene. The novel method comprises the following steps: by taking dichloroethane as a solvent and aluminum trichloride as a catalyst, enabling fluorene and 2-chloro-2-methylpropane to be in Friedel-Crafts reaction to obtain a 2,7-di-tert-butyl fluorene crude product; carrying out bromination on the 2,7-di-tert-butyl fluorene crude product by virtue of a high-selectivity bromination reagent to obtain 2,7-di-tert-butyl-4-bromofluorene; removing tertiary butyl from the 2,7-di-tert-butyl-4-bromofluorene by virtue of lewis acid to obtain 4-bromofluorene; re-crystallizing with alcohol at a reaction temperature of 10 DEG C-50 DEG C to obtain 4-bromofluorene. The 4-bromofluorene prepared by the method is high in purity and has GC purity of 99.9%, dibromofluorene content less than 100ppm and good application prospect.

Gold(I) carbenes by retro-buchner reaction: Generation and fate

The fate of the aryl gold(I) carbenes generated by retro-Buchner reaction of ortho-substituted 7-aryl-1,3,5-cycloheptatrienes is dependent on the constitution of the ortho substituent. Indenes and fluorenes are obtained by intramolecular reaction of highly electrophilic gold(I) carbenes with alkenes and arenes. According to density functional theory calculations, the gold-catalyzed retro-Buchner process occurs stepwise, although the two carbon-carbon cleavages occur on a rather flat potential energy surface.

Catalyst components and their use in the polymerization of olefins

Catalyst compositions and processes for the polymerization of ethylenically unsaturated monomers to produce polymers specific to the polymerization of propylene to produce isotactic polypropylene and copolymer, specifically an ethylene-propylene copolymer

Selective Preparation of Fluorene Derivatives Using the t-Butyl Function as a Positional Protective Group

Several 4-substituted 2,7-di-t-butylfluorene derivatives (3) were prepared by electrophilic substitutions of 2,7-di-t-butylfluorene (1). 4-Substituted fluorene (4), such as 4-bromo- (4a), 4-methyl (4e), and 4-aacetylaminofluorene (4j), were obtained by the trans-t-butylations of 3.Although we attempted to synthesize 1,8-disubstituted fluorene from 3,6-di-t-butylfluorene (2) which was derived from 2,2'-diiodo-4,4'-di-t-butyldiphenylmethane (5), by the same methods, we obtained only 2,7-disubstituted fluorene derivatives (8); it turned out electrophilic substitutions of 2 gave 2,7-disubstituted 3,6-di-t-butylfluorene derivatives.