Synthesis and Biological Evaluation of New Eugenol Mannich Bases as Promising Antifungal Agents
New Mannich base-type eugenol derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 4-allyl-2-methoxy-6-(morpholin-4-ylmethyl) phenyl benzoate (7) and 4-{5-allyl-2-[(
Abr?o, Pedro Henrique O.,Pizi, Rafael B.,De Souza, Thiago B.,Silva, Naiara C.,Fregnan, Antonio M.,Silva, Fernanda N.,Coelho, Luiz Felipe L.,Malaquias, Luiz Cosme C.,Dias, Amanda Latercia T.,Dias, Danielle F.,Veloso, Marcia P.,Carvalho, Diogo T.
Design, synthesis, biological evaluation and molecular modeling studies of novel eugenol esters as leishmanicidal agents
Leishmaniasis is a neglected pathology with a high incidence worldwide, and is a governmental health issue due to the increased morbidity and mortality associated with the disease and a scarce therapeutic arsenal. Cysteine proteases have been investigated
Coelho, Camila M.,Dos Santos, Thiago,Freitas, Poliany G.,Nunes, Juliana B.,Marques, Marcos J.,Padovani, Camila G. D.,Júdice, Wagner A. S.,Camps, Ihosvany,Da Silveira, Nelson J. F.,Carvalho, Diogo T.,Veloso, Marcia P.
p. 715 - 728
(2018/02/07)
NEW PHENOLIC ETHERS. II. SYNTHESIS AND PHARMACOLOGY OF ETHERS OF BASIC PHENOLS.
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PALA,CRESCENZI,TURBA,FRESIA
p. 324 - 335
(2007/10/04)
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