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CAS

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19893-78-8

AAMU, or alpha-aminomuconic acid, is a chemical compound that belongs to the group of aminobenzoic acid. It is a key intermediate in the metabolism of the amino acid tryptophan and is an important precursor for the biosynthesis of the pigment melanin. AAMU has also been studied for its potential role in the development of Parkinson's disease due to its ability to form toxic quinones which can damage dopaminergic neurons. Additionally, AAMU has been identified as a potential biomarker for exposure to environmental toxins such as benzene. Overall, the chemical AAMU has been the subject of research for its role in various physiological processes and its potential implications for human health.
Usage:
Used in Pharmaceutical Industry:
AAMU is used as a precursor for the biosynthesis of melanin, which is an important pigment in the human body. Its role in melanin production makes it a potential target for the development of treatments for pigmentation disorders and other related conditions.
Used in Neurological Research:
AAMU is used as a potential biomarker for exposure to environmental toxins such as benzene. Its identification as a biomarker can help in the assessment of exposure levels and the development of preventive measures against the harmful effects of these toxins.
Used in Parkinson's Disease Research:
AAMU is used as a potential factor in the development of Parkinson's disease due to its ability to form toxic quinones which can damage dopaminergic neurons. Its role in the disease process makes it a subject of research for the development of therapeutic interventions and preventive strategies.
Used in Environmental Toxicology:
AAMU is used as a potential biomarker for exposure to environmental toxins, which can help in the assessment of exposure levels and the development of preventive measures against the harmful effects of these toxins. Its identification as a biomarker can aid in the understanding of the mechanisms of toxicity and the development of strategies to mitigate the risks associated with exposure to these toxins.

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  • 19893-78-8 Structure

  • Basic information

    1. Product Name: AAMU
    2. Synonyms: 5-Acetylamino-6-amino-3-methyluracil, N-(4-Amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)acetimide;N-(4-Amino-2,6-dioxo-1-methyl-1,2,3,6-tetrahydropyrimidin-5-yl)acetamide;5-Ammu;Acetamide, N-(4-amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)-;5-Acetylamino-6-amino-3-methyluracil-[13C4,15N3] (AAMU);5-AcetylaMino-6-aMino-3-Methyluracil (AAMU);1,3-15N2,6-AMINO-15N,98%);5-ACETYLAMINO-6-AMINO-3-METHYLURACIL (AAMU) CP 97 (2,4,5,6-13C4.99%
    3. CAS NO:19893-78-8
    4. Molecular Formula: C7H10N4O3
    5. Molecular Weight: 198.181
    6. EINECS: N/A
    7. Product Categories: Isolabel
    8. Mol File: 19893-78-8.mol

  • Chemical Properties

    1. Melting Point: ≥305 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: white to light pink/
    5. Density: 1.45g/cm3
    6. Refractive Index: 1.606
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: AAMU(CAS DataBase Reference)
    10. NIST Chemistry Reference: AAMU(19893-78-8)
    11. EPA Substance Registry System: AAMU(19893-78-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 19893-78-8(Hazardous Substances Data)

19893-78-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 19893-78-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,8,9 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19893-78:
(7*1)+(6*9)+(5*8)+(4*9)+(3*3)+(2*7)+(1*8)=168
168 % 10 = 8
So 19893-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N4O3/c1-3(12)9-4-5(8)10-7(14)11(2)6(4)13/h8H2,1-2H3,(H,9,12)(H,10,14)

19893-78-8 Well-known Company Product Price

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  • Sigma

  • (UC432)  AAMU  

  • 19893-78-8

  • UC432-5MG

  • 12,577.50CNY

  • Detail

  • Sigma

  • (UC432)  AAMU  

  • 19893-78-8

  • UC432-10MG

  • 23,341.50CNY

  • Detail

19893-78-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(6-amino-3-methyl-2,4-dioxo-1H-pyrimidin-5-yl)acetamide

1.2 Other means of identification

Product number -
Other names Acetamide,N-(4-amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19893-78-8 SDS

19893-78-8Relevant articles and documents

Preparation of guanine PDE inhibitors: Development of the common synthetic route strategy. A case study

Gala,DiBenedetto,Gloor,Jenkins,Kugelman,Maloney,Miller

, p. 396 - 400 (2004)

A single synthetic route, called the chloropurine route, capable of quickly delivering initial kilogram quantities of several chiral as well as achiral guanine phosphodiesterase inhibitors of increasing complexity is described. During the course of this w

Synthesis of the caffeine metabolites 5-acetylamino-6-formylamino-3-methyluracil (AFMU) and 5-acetylamino-6-amino-3-methyluracil (AAMU) on a preparative scale

Roehrkasten,Raatz,Kreher,Blaszkewicz

, p. 1526 - 1532 (2007/10/03)

5-Acetylamino-6-amino-3-methyluracil (AAMU) and 5-acetylamino-6-formylamino-3-methyluracil (AFMU) have been prepared by simple chemical transformations starting from thiourea and ethyl cyanoacetate. These compounds AAMU and AFMU are required as standard m

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