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6-Boc-2-oxo-6-aza-spiro[3.4]octane is a spirocyclic chemical compound with the molecular formula C13H21NO4. It features a spiro[3.4]octane ring system, a tert-butoxycarbonyl (Boc) protecting group at the sixth position, a ketone group at the second position, and a nitrogen atom at the sixth position. 6-Boc-2-oxo-6-aza-spiro[3.4]octane is of interest in the fields of organic synthesis and medicinal chemistry.

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  • 203661-71-6 Structure
  • Basic information

    1. Product Name: 6-Boc-2-oxo-6-aza-spiro[3.4]octane
    2. Synonyms: 6-Boc-2-oxo-6-aza-spiro[3...;2-Oxo-6-aza-spiro[3.4]octane-6-carboxylic acid tert-butyl-ester;2-oxo-6-Azaspiro[3.4]octane-6-carboxylic acid 1,1-dimethylethyl ester;6-Azaspiro[3.4]octan-2-one,N-BOCprotected;6-N-Boc-2-oxo-6-aza-spiro[3.4]octane;6-Azaspiro[3.4]octane-6-carboxylic acid, 2-oxo-, 1,1-dimethylethyl ester;tert-Butyl 2-oxo-7-azaspiro[3.4]octane-7-carboxylate;6-Boc-2-oxo-6-aza-spiro[3.4]octane
    3. CAS NO:203661-71-6
    4. Molecular Formula: C12H19NO3
    5. Molecular Weight: 225.28416
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 203661-71-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 331.8±35.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.14±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: -0.80±0.20(Predicted)
    10. CAS DataBase Reference: 6-Boc-2-oxo-6-aza-spiro[3.4]octane(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-Boc-2-oxo-6-aza-spiro[3.4]octane(203661-71-6)
    12. EPA Substance Registry System: 6-Boc-2-oxo-6-aza-spiro[3.4]octane(203661-71-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 203661-71-6(Hazardous Substances Data)

203661-71-6 Usage

Uses

Used in Organic Synthesis:
6-Boc-2-oxo-6-aza-spiro[3.4]octane is used as a building block in organic synthesis for the creation of complex molecules. Its unique structure and functional groups make it a versatile component in the assembly of various organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-Boc-2-oxo-6-aza-spiro[3.4]octane is utilized as a precursor for the development of pharmaceuticals. Its structural features can be exploited to design and synthesize new drug candidates with potential therapeutic applications.
Used in Pharmaceutical Development:
6-Boc-2-oxo-6-aza-spiro[3.4]octane is used as a key intermediate in the synthesis of pharmaceuticals, particularly for the development of novel drugs targeting specific biological pathways or receptors. Its presence in the molecular structure can influence the pharmacokinetic and pharmacodynamic properties of the final drug product.
Used in Chemical Research:
6-Boc-2-oxo-6-aza-spiro[3.4]octane serves as a subject of study in chemical research, where its reactivity, stability, and potential applications are explored. Understanding its properties can lead to the discovery of new reactions or processes that involve this compound.
Used in the Synthesis of Bioactive Molecules:
6-Boc-2-oxo-6-aza-spiro[3.4]octane is employed in the synthesis of bioactive molecules with potential applications in medicine, such as antimicrobial, antiviral, or anticancer agents. Its incorporation into these molecules can enhance their biological activity or selectivity.

Check Digit Verification of cas no

The CAS Registry Mumber 203661-71-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,3,6,6 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 203661-71:
(8*2)+(7*0)+(6*3)+(5*6)+(4*6)+(3*1)+(2*7)+(1*1)=106
106 % 10 = 6
So 203661-71-6 is a valid CAS Registry Number.

203661-71-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 2-oxo-6-azaspiro[3.4]octane-6-carboxylate

1.2 Other means of identification

Product number -
Other names C-8886

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:203661-71-6 SDS

203661-71-6Relevant articles and documents

CHEMICAL COMPOUNDS

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Paragraph 0110-0112, (2021/04/02)

The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the disclosure have activity as Janus kinase (JAK) inhibitors and are useful in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK by administering a compound herein described.

PYRAZOLE COMPOUNDS AS BTK INHIBITORS

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Page/Page column 24; 25, (2015/09/23)

The present invention encompasses compounds of the formula (I) wherein the groups R1, Cy, and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS

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Paragraph 0113, (2014/03/21)

The present invention encompasses compounds of the formula (I) wherein the groups A, Cy, X1 and Y are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS

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Paragraph 0128; 0129; 0132, (2014/09/29)

The present invention encompasses compounds of the formula (I) wherein the groups X and Cy are defined herein, which are suitable for the treatment of diseases related to BTK, process of making, pharmaceutical preparations which contain compounds and their methods of use.

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