204185-34-2

Basic information

• Product Name: 4-THIAZOLEACETIC ACID, 2-AMINO-ALPHA-[[2-(1,1-DIMETHYLETHOXY)-2-OXOETHOXY]IMINO]-, ANHYDRIDE WITH DIETHYL HYDROGEN PHOSPHATE, (Z)-
• Synonyms: PTMA:O,O-DIETHYLPHOSPHORYL ( Z )-2-(2-AMINOTHIAZOL-4-YL)-2-(T-BUTOXYCARBONYLMETHOXYIMINO)ACETATE;4-THIAZOLEACETIC ACID, 2-AMINO-ALPHA-[[2-(1,1-DIMETHYLETHOXY)-2-OXOETHOXY]IMINO]-, ANHYDRIDE WITH DIETHYL HYDROGEN PHOSPHATE, (Z)-;O,O-DIETHYLPHOSPHORYL (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-(T-BUTOXYCARBONYLMETHOXYIMINO)ACETATE;PTMA
• CAS NO: 204185-34-2
• Molecular Formula: C₁₅H₂₄N₃O₈PS
• Molecular Weight: 437.41
• Mol File: 204185-34-2.mol

Chemical Properties

• Boiling Point: 521.195°C at 760 mmHg
• Flash Point: 269.009°C
• Appearance: /
• Density: 1.402g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 4-THIAZOLEACETIC ACID, 2-AMINO-ALPHA-[[2-(1,1-DIMETHYLETHOXY)-2-OXOETHOXY]IMINO]-, ANHYDRIDE WITH DIETHYL HYDROGEN PHOSPHATE, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-THIAZOLEACETIC ACID, 2-AMINO-ALPHA-[[2-(1,1-DIMETHYLETHOXY)-2-OXOETHOXY]IMINO]-, ANHYDRIDE WITH DIETHYL HYDROGEN PHOSPHATE, (Z)-(204185-34-2)
• EPA Substance Registry System: 4-THIAZOLEACETIC ACID, 2-AMINO-ALPHA-[[2-(1,1-DIMETHYLETHOXY)-2-OXOETHOXY]IMINO]-, ANHYDRIDE WITH DIETHYL HYDROGEN PHOSPHATE, (Z)-(204185-34-2)

Safety Data

• Hazardous Substances Data: 204185-34-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-, anhydride with diethyl hydrogen phosphate, (Z)is used as a pharmaceutical intermediate for the synthesis of various drug molecules. Its unique structure and properties allow it to participate in specific chemical reactions, enabling the development of new therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-, anhydride with diethyl hydrogen phosphate, (Z)is utilized as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its structural features and reactivity contribute to the development of effective and targeted agrochemical products, enhancing crop protection and yield.
Used as a Catalyst in Chemical Processes:
4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-, anhydride with diethyl hydrogen phosphate, (Z)also serves as a catalyst in various chemical reactions. Its unique structure allows it to facilitate specific transformations, improving the efficiency and selectivity of the reactions, and enabling the synthesis of desired products with minimal side reactions or byproducts.

InChI:InChI=1/C15H24N3O8PS/c1-6-23-27(21,24-7-2)26-13(20)12(10-9-28-14(16)17-10)18-22-8-11(19)25-15(3,4)5/h9H,6-8H2,1-5H3,(H2,16,17)/b18-12-

Upstream product

• 814-49-3 diethyl chlorophosphate 
• 74440-02-1 (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[[2-(tert-butoxy)-2-oxoethoxy]imino]acetic acid 

Relevant articles and documents

Diethyl chlorophosphate: An effective and convenient coupling reagent of cephalosporin derivatives

A coupling reagent, diethyl chlorophosphate (DECP) 2, was reacted with 2-(2-amino-4-thiazolyl)-2-syn-alkoxyiminoacetic acid 1 to give an active ester intermediate 3.