204691-99-6 Usage
Uses
Used in Organic Synthesis:
4-Benzamido-cyclohexanol is used as a reagent for its ability to act as a chiral auxiliary, which is crucial in the asymmetric synthesis of various organic compounds. This application is significant in producing enantiomerically pure products, a key factor in many pharmaceutical and chemical industries where the stereochemistry of molecules can affect their biological activity.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-Benzamido-cyclohexanol is used as a starting material or intermediate in the development of new drugs. Its potential pharmacological activities, such as being an analgesic and anti-inflammatory agent, make it a promising candidate for further research and development in medicinal chemistry.
Used in Drug Discovery:
4-Benzamido-cyclohexanol's unique structure and reactivity also make it a valuable tool in drug discovery. Researchers can use 4-Benzamido-cyclohexanol to explore new chemical spaces and potentially identify novel therapeutic agents with improved efficacy and selectivity. This application is particularly relevant in the ongoing quest to find new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 204691-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,6,9 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 204691-99:
(8*2)+(7*0)+(6*4)+(5*6)+(4*9)+(3*1)+(2*9)+(1*9)=136
136 % 10 = 6
So 204691-99-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO2/c15-12-8-6-11(7-9-12)14-13(16)10-4-2-1-3-5-10/h1-5,11-12,15H,6-9H2,(H,14,16)
204691-99-6Relevant articles and documents
N-heterocyclic carbene-catalyzed oxidative amidation of aldehydes with amines
Alanthadka, Anitha,Maheswari, C. Uma
supporting information, p. 1199 - 1203 (2015/04/22)
The N-heterocyclic carbene (NHC)-catalyzed oxidative amidation of aromatic aldehydes with amines in the presence of N-bromosuccinimide (NBS) as an oxidant has been developed for the synthesis of amides. This amidation strategy is tolerant to both the electronic and the steric nature of the aryl aldehydes employed. The present methodology was extended to chiral amino acid derivatives to generate the corresponding amides in good yields and excellent ee values (>98%).
Iron-catalyzed efficient synthesis of amides from aldehydes and amine hydrochloride salts
Ghosh, Subhash Chandra,Ngiam, Joyce S. Y.,Chai, Christina L. L.,Seayad, Abdul M.,Dang, Tuan Thanh,Chen, Anqi
supporting information; experimental part, p. 1407 - 1412 (2012/07/13)
A practical and efficient method for the synthesis of amides has been developed by iron-catalysed oxidative amidation of aldehydes with amine hydrochloride salts. A wide range of amides have been obtained in good to excellent yields under mild conditions. The application of this novel amide formation reaction to the synthesis of pharmaceutical compounds has been successfully demonstrated. Copyright
Synthesis and microbial hydroxylation of some azabicycloalkanes
Olivo, Horacio F.,Hemenway, Michael S.,Gezginci, Mikail H.
, p. 1309 - 1312 (2007/10/03)
N-Substituted 7-azabicyclo[2.2.1]heptanes have been synthesized in a short route. These compounds containing benzamide or benzenesulfonamide groups are good substrates for microbial oxidation of unactivated carbons by B. bassiana.
