205582-88-3

Basic information

• Product Name: METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE
• Synonyms: METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE;3-(Ethoxycarbonyl)-2-methyl-6-(trifluoromethyl)pyridine
• CAS NO: 205582-88-3
• Molecular Formula: C₉H₈F₃NO₂
• Molecular Weight: 219.16
• Mol File: 205582-88-3.mol

Chemical Properties

• Boiling Point: 209.0±40.0 °C(Predicted)
• Appearance: /
• Density: 1.286±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -0.78±0.22(Predicted)
• CAS DataBase Reference: METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE(205582-88-3)
• EPA Substance Registry System: METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE(205582-88-3)

Safety Data

• Hazardous Substances Data: 205582-88-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE is used as a therapeutic agent for its potential antiviral and anti-inflammatory properties. Its unique chemical structure allows it to target specific biological pathways, making it a promising candidate for the development of new drugs to treat various diseases.
Used in Agrochemical Industry:
METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE is used as a pesticidal agent for its insecticidal and fungicidal activities. Its ability to control pests and diseases in crops can contribute to increased agricultural productivity and crop protection.
The trifluoromethyl group in METHYL 2-METHYL-6-(TRIFLUOROMETHYL)NICOTINATE may enhance its bioactivity and metabolic stability, making it a valuable compound in drug discovery and agricultural applications. This feature allows for the development of more effective and longer-lasting treatments and pesticides, ultimately benefiting both human health and agricultural practices.

Upstream product

• 120417-45-0 4-amino-1,1,1-trifluoro-3-buten-2-one 
• 105-45-3 acetoacetic acid methyl ester 
• 184848-89-3 4-amino-1,1,1-trifluorobuten-2-one 
• 39971-65-8 bis(((trifluoromethyl)sulfinyl)oxy)zinc 
• 65719-09-7 methyl 2-methylnicotinate 
• 400-36-2 trifluoroacetylacetic acid 
• 122-51-0 orthoformic acid triethyl ester 
• 14205-39-1 methyl 3-aminocrotonate 

Downstream Products

• 261635-98-7 2-methyl-6-(trifluoromethyl)-3-pyridinecarbonyl chloride 
• 681260-50-4 (2-methyl-6-(trifluoromethyl)pyridin-3-yl)methanol 
• 261635-93-2 2-methyl-6-(trifluoromethyl)pyridine-3-carboxylic acid 
• 917481-91-5 6-chloro-5-(4-chlorophenyl)-2-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-4-(pyridin-4-yl)-pyridazin-3(2H)-one 
• 917969-46-1 8-bromo-7-(4-chlorophenyl)-2-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 917969-39-2 4-(8-bromo-2-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-3-oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-7-yl)benzonitrile 
• 917968-89-9 3-((7-(4-chlorophenyl)-3-oxo-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)methyl)-2-methyl-6-(trifluoromethyl)pyridine 1-oxide 
• 917969-50-7 3-((7-(4-chlorophenyl)-3-oxo-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)methyl)-6-(trifluoromethyl)picolinoyl chloride 

Relevant articles and documents

Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from 4,4,4-trifluoro-3-aminobutanoates

The invention discloses a method for the preparation of substituted 6-trifluoromethylpyridine-3-carboxylic acid derivatives starting from 4,4,4-trifluoro-3-aminobutanoates and proceeding via enamines and dihydropyridinones.

METHOD FOR PREPARATION OF 6-TRIFLUOROMETHYLPYRIDINE-3-CARBOXYLIC ACID DERIVATIVES FROM TRIFLUOROACETYLACETIC ACID

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Method for preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives

The invention discloses a method for the preparation of substituted 6-trifluoromethylpyridine-3-carboxylic acid derivatives starting from 1,1,1-trifluoroacetone or from synthetic equivalents of 1,1,1-trifluoroacetone.

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