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2-Fluoro-3-(trifluoromethyl)benzamide is a chemical compound characterized by the molecular formula C8H5F4NO. It is a benzamide derivative featuring a fluoro and a trifluoromethyl group attached to a benzene ring. 2-Fluoro-3-(trifluoromethyl)benzamide is recognized for its unique structure and properties, which render it a valuable asset in the fields of organic synthesis and pharmaceutical research. Its fluorinated nature allows for the exploration of the effects of these functional groups on biological and chemical systems, making it a promising candidate for the development of innovative drugs and materials.

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  • 207853-60-9 Structure
  • Basic information

    1. Product Name: 2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE
    2. Synonyms: BUTTPARK 45\01-73;2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE;ALPHA,ALPHA,ALPHA,2-TETRAFLUORO-M-TOLUAMIDE;à,à,à,2-tetrafluoro-m-toluamide;α,α,α,2-tetrafluoro-m-toluamide;2-Fluoro-3-(trifluoromethyl)benzamide 97%;2-Fluoro-3-(trifluoromethyl)benzamide97%
    3. CAS NO:207853-60-9
    4. Molecular Formula: C8H5F4NO
    5. Molecular Weight: 207.13
    6. EINECS: N/A
    7. Product Categories: Fluorine series
    8. Mol File: 207853-60-9.mol
  • Chemical Properties

    1. Melting Point: 94-97 °C(lit.)
    2. Boiling Point: 211℃
    3. Flash Point: 81℃
    4. Appearance: /
    5. Density: 1.420
    6. Vapor Pressure: 0.352mmHg at 25°C
    7. Refractive Index: 1.462
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. PKA: 14.58±0.50(Predicted)
    11. CAS DataBase Reference: 2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE(207853-60-9)
    13. EPA Substance Registry System: 2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE(207853-60-9)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 207853-60-9(Hazardous Substances Data)

207853-60-9 Usage

Uses

Used in Organic Synthesis:
2-Fluoro-3-(trifluoromethyl)benzamide serves as a versatile building block in organic synthesis, where its fluorinated groups can be utilized to create a variety of complex organic molecules. The presence of the fluoro and trifluoromethyl groups enhances the reactivity and selectivity of the compound, facilitating the synthesis of new chemical entities with potential applications in various industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Fluoro-3-(trifluoromethyl)benzamide is employed as a key intermediate in the development of new drugs. Its unique structure allows for the fine-tuning of pharmacological properties, such as potency, selectivity, and metabolic stability. 2-Fluoro-3-(trifluoromethyl)benzamide's fluorinated groups can significantly influence the drug's binding affinity to target proteins, potentially leading to the discovery of more effective therapeutic agents.
Used in Material Science:
2-Fluoro-3-(trifluoromethyl)benzamide also finds applications in material science, where its fluorinated groups can impart specific properties to newly developed materials. For instance, the introduction of fluorine atoms can enhance the thermal stability, chemical resistance, and electronic properties of polymers and other materials, broadening their potential uses in high-performance applications.
Used in Biological and Chemical Systems Research:
The presence of the fluoro and trifluoromethyl groups in 2-Fluoro-3-(trifluoromethyl)benzamide makes it an interesting subject for studying their effects on biological and chemical systems. Researchers can use this compound to investigate how fluorination impacts molecular interactions, enzymatic activities, and the overall behavior of chemical systems, providing valuable insights into the role of fluorine in chemical and biological processes.

Check Digit Verification of cas no

The CAS Registry Mumber 207853-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,8,5 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 207853-60:
(8*2)+(7*0)+(6*7)+(5*8)+(4*5)+(3*3)+(2*6)+(1*0)=139
139 % 10 = 9
So 207853-60-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F4NO/c9-6-2-1-4(8(10,11)12)3-5(6)7(13)14/h1-3H,(H2,13,14)

207853-60-9 Well-known Company Product Price

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  • Alfa Aesar

  • (L10135)  2-Fluoro-3-(trifluoromethyl)benzamide, 97%   

  • 207853-60-9

  • 1g

  • 444.0CNY

  • Detail
  • Alfa Aesar

  • (L10135)  2-Fluoro-3-(trifluoromethyl)benzamide, 97%   

  • 207853-60-9

  • 5g

  • 1516.0CNY

  • Detail

207853-60-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-FLUORO-3-(TRIFLUOROMETHYL)BENZAMIDE

1.2 Other means of identification

Product number -
Other names 2-Fluoro-3-trifluoromethyl-benzamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:207853-60-9 SDS

207853-60-9Relevant articles and documents

2-chloro-3-fluoro-4-(trifluoromethyl) benzaldehyde and synthesis method thereof

-

Paragraph 0018; 0020; 0022; 0030; 0032; 0034, (2021/04/10)

The invention belongs to the technical field of pesticide intermediates, and particularly relates to 2-chloro-3-fluoro-4-(trifluoromethyl) benzaldehyde. The invention discloses unreported 2-chloro-3-fluoro-4-(trifluoromethyl) benzaldehyde and a synthetic method thereof. In the synthesis process, the product is formed through reaction under normal pressure, the process is simple, industrial application is facilitated, reaction conditions are mild, operation is easy, and the industrial production requirement is met; the 2-chloro-3-fluoro-4-(trifluoromethyl) benzaldehyde disclosed by the invention can be widely applied to a pesticide synthesis process, such as synthesis of pesticides such as herbicides and the like, and is relatively high in synthesis yield and relatively high in purity.

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