20900-22-5

Basic information

• Product Name: 1-Bromo-4-ethoxynaphthalene
• Synonyms: 1-Bromo-4-ethoxynaphthalene;1-Bromo-4-ethoxynaphthalene（WS203254）
• CAS NO: 20900-22-5
• Molecular Formula: C₁₂H₁₁BrO
• Molecular Weight: 251.11914
• Mol File: 20900-22-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Bromo-4-ethoxynaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-4-ethoxynaphthalene(20900-22-5)
• EPA Substance Registry System: 1-Bromo-4-ethoxynaphthalene(20900-22-5)

Safety Data

• Hazardous Substances Data: 20900-22-5(Hazardous Substances Data)

Usage

Structure

Brominated derivative of naphthalene with a bromine atom and an ethoxy group attached to the 4-position of the naphthalene ring

Usage

Reagent in organic synthesis, building block for the synthesis of various pharmaceutical and agrochemical compounds

Properties

Aromatic

Handling precautions

Potentially hazardous if not properly handled and stored.

Upstream product

• 74-96-4 ethyl bromide 
• 571-57-3 4-bromo-1-naphthol 
• 5328-01-8 1-ethoxynaphthalene 
• 7789-69-7 phosphorus pentabromide 
• 7726-95-6 bromine 
• 90-15-3 α-naphthol 
• 75-03-6 ethyl iodide 

Downstream Products

• 90-15-3 α-naphthol 

Relevant articles and documents

Facile synthesis of lipophilic δ-amino acid conjugates from 4-alkoxy-dithionaphthoic acids

(Chemical Equation Presented) Novel 4-alkoxy-dithionaphthoic acids were prepared and shown to be valuable synthons for δ-amino acid conjugates. These dithioacids are efficiently synthesized and purified, stable to storage, and easily derivatized to facilitate thioacylation chemistry. To this end, we have demonstrated dithionaphthoic acids (6) to successfully undergo coupling with both protected and unprotected amino acids, giving rise to stable thioamide conjugates (8 and 9). Copyright Taylor & Francis Group, LLC.

Regioselective Halogenation and Dimerization of Alkoxynaphathalenes with Alumina- or Kieselguhr-supported Copper(II) Halides

The reaction of 1-alkoxynaphathalenes 1 with alumina-supported copper(II) bromide or copper(II) chloride gave dimers, 4,4'-dialkoxy-1,1'-binaphthyls 3, as major products, and with Kieselguhr-supported copper(II) bromide afforded 1-bromo-4-alkoxynaphthalenes 2, while the reaction of 2-alkoxynaphathalenes 4 with alumina- or Kieselguhr-supported copper(II) bromide gave preferentially 1-bromo-2-alkoxynaphthalenes 5.