cas 2103-95-9, 37(4-BROMOPHENYL)-2-THIAZOLETHIOL

Articles about 2103-95-9Total 7 be found

Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes
To explore a new skeleton with nematicidal activity, a series of novel azabicyclo derivatives containing a thiazole moiety were designed, synthesized and evaluated for their nematicidal activities. The bioassay results against pine-wood nematodes (Bursaphelenchus xylophilus) showed that most of the title compounds displayed nematicidal activity at a concentration of 40 mg/L. Especially, the title compounds2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-4-(4-chlorophenyl)thiazole (7e), 2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)-4-phenylthiazole (10a) and 2-((8-methyl-8-azabicyclo [3.2.1]octan-3-yl)thio)-4-(4-chlorophenyl)thiazole (10e) exhibited more than 90% mortality against Bursaphelenchus xylophilus.
Li, Hui,Lu, Aoyun,Zhang, Yanqiu,Peng, Yanqing,Song, Gonghua
p. 371 - 375
(2020/01/02)

Synthesis of 4- and 5-arylthiazolinethiones as inhibitors of indoleamine 2,3-dioxygenase
Docking studies of 4-phenylthiazolinethione on human IDO1 suggest complexation of the heme iron by the exocyclic sulfur atom further reinforced by hydrophobic interactions of the phenyl ring within pocket A of the enzyme. On this basis, chemical modifications were proposed to increase inhibition activity. Synthetic routes had to be adapted and optimized to yield the desired substituted 4- and 5-arylthiazolinethiones. Their biological evaluation shows that 5-aryl regioisomers are systematically less potent than the corresponding 4-aryl analogs. Substitution on the phenyl ring does not significantly increase inhibition potency, except for 4-Br and 4-Cl derivatives.
Balti, Monaem,Plas, Aurélie,Meinguet, Céline,Haufroid, Marie,Thémans, Quentin,Efrit, Mohamed Lotfi,Wouters, Johan,Lanners, Steve
supporting information
p. 3607 - 3610
(2017/07/07)

Synthesis new and novel aryl thiazole derivatives compounds
Six new compounds of Thiazoles family was synthesis from condensation reaction of some compounds from pyrazolines. NMR, IR and elemental analysis was used for identification of these compounds. Position of aliphatic and aromatic hydrogens in pyrazolone and thiazole cycles had established proceeding of identification. Most of obtained compounds like aciform crystals, their color is white and yellow. Reaction time and yield of these compounds had shown better results as compared with other thiazole derivations.
Akbarzadeh, Abolfath,Soleymani, Reza,Taheri, Milad,Ali, Maryam Karimi-Cheshmeh
p. 153 - 164
(2012/09/07)

Synthesis, NMR, vibrational and mass spectroscopy with DFT/HF studies of 4-(4/-Bromophenyl) -2-Mercaptothiazole Structure
Ammonium dithiocarbamate was combined with a compound of phenacylbromide family; 4-(4/-Bromophenyl)-2-mercaptothiazole structure was synthesized. The spectroscopic properties of this structure were studied using 1H-NMR, 13C-NMR, FT-IR, Mass Spectroscopy a
Soleymani, Reza,Salehi, Yasin Mohammad,Yousofzad, Tahereh,Ali, Maryam Karimi-Cheshmeh
p. 627 - 638,12
(2020/08/24)

A facile synthesis of thiazole-2(3H)-thiones through [hydroxy(tosyloxy) iodo]benzene
A one-pot facile synthesis of thiazole-2(3H)-thiones (4) has been achieved by hypervalent iodine oxidation of ketones (1) using [hydroxy (tosyloxy)iodo]benzene, followed by the treatment of the reaction mixture with dithiocarbamate salts (3) The intermediate α-tosyloxy-ketones (2) have also been isolated and converted to the target compounds.
Aggarwal, Ranjana,Pundeer, Rashmi,Kumar, Vinod,Chaudhri, Vishwas,Singh, Shiv P.,Prakash, Om
p. 2659 - 2664
(2007/10/03)

Hypervalent iodine in synthesis. 48. A one-pot convenient procedure for the synthesis of 2-mercaptothiazoles by cyclocondensation of ketones with [hydroxy(tosyloxy)iodo]-benzene and ammonium dithiocarbamate
α-Tosyloxylation of ketones with [hydroxy(tosyloxy)iodo]-benzene (HTIB), followed by treatment with ammonium dithiocarbamate, provides a one-pot convenient procedure for the synthesis of 2-mercaptothiazoles with good yields.
Zhang,Chen
p. 415 - 420
(2007/10/03)

Hypervalent iodine in synthesis; 60: A novel method for the synthesis of 2-mercaptothiazoles by cyclocondensation of alkynyl(phenyl)iodonium salts and ammonium dithiocarbamate
A novel method for the synthesis of 2-mercaptothiazoles is achieved by cyclocondensation of alkynyl(phenyl)iodonium salts with ammonium dithiocarbamate. A reaction mechanism is proposed.
Zhang,Chen
p. 358 - 360
(2007/10/03)