98475-05-9

Upstream product

• 4203-30-9 1-(4-bromo-phenyl)-2-diazo-ethanone 
• 104-15-4 toluene-4-sulfonic acid 
• 27126-76-7 [hydroxy(tosyloxy)iodo]benzene 
• 99-90-1 para-bromoacetophenone 
• 159950-96-6 1-(p-methylbenzenesulfonyloxy)-1,2-benziodoxol-3(1H)-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 5391-88-8 1-(4-bromophenyl)ethanol 

Downstream Products

• 141421-06-9 3-(4-Bromo-phenyl)-5,6-dihydro-imidazo[2,1-b]thiazole; compound with toluene-4-sulfonic acid 
• 2103-94-8 4-(4-bromophenyl)-1,3-thiazol-2-amine 
• 142739-60-4 1-(4-bromophenyl)-2-(4-methoxyphenylamino)ethanone 
• 62558-60-5 1-(4-bromophenyl)-2-(phenylamino)ethanone 
• 111946-84-0 1-(4-Bromo-phenyl)-2-(4-nitro-phenoxy)-ethanone 
• 36234-86-3 α-(4-methylphenoxy)-4-bromoacetophenone 
• 35345-13-2 4-(4-bromophenyl)-2-phenyl-1H-imidazole 
• 34658-66-7 2-(4-bromophenyl)imidazo[1,2-a]pyridine 
• 2103-95-9 4-(4-bromophenyl)thiazole-2-thione 
• 51655-92-6 4-(4-bromo-phenyl)-3-phenyl-3H-thiazole-2-thione 
• 61001-06-7 2-(4-bromophenyl)imidazo<2,1-a>isoquinoline 
• 38758-84-8 2-(4-bromo-phenyl)-9-[2-(4-bromo-phenyl)-2-oxo-ethyl]-9H-benzo[d]imidazo[1,2-a]imidazole 
• 58881-56-4 2,2'-thiobis[1-(4-bromophenyl)ethanone] 
• 1174679-00-5 5-(4-bromophenyl)-2-phenyl-6H-1,3,4-oxadiazine 

Relevant academic research and scientific papers

Diastereoselective Alkene Hydroesterification Enabling the Synthesis of Chiral Fused Bicyclic Lactones

Palladium-catalysed diastereoselective hydroesterification of alkenes assisted by the coordinative hydroxyl group in the substrate afforded a variety of chiral γ-butyrolactones bearing two stereocenters. Employing the carbonylation-lactonization products as the key intermediates, the route from the alkenes with single chiral center to chiral THF-fused bicyclic γ-lactones containing three stereocenters was developed.

Synthesis method of alpha-carbonyl sulfonate and catalyst used in synthesis method

The invention provides a nitrogen and carbon co-doped Nb2O5 catalyst for synthesizing alpha carbonyl sulfonate, a preparation method of the nitrogen and carbon co-doped Nb2O5 catalyst, and a synthesizing method of the alpha carbonyl sulfonate by using the catalyst under the driving of visible light. Based on the total weight of the catalyst, the content of nitrogen is 0.01 wt%-1wt%; the content of the carbon is 0.01 wt% to 1.5 wt%. The catalyst provided by the invention is used for preparing alpha-carbonyl sulfonate through olefin aerobic oxidation, the reaction condition is mild, oxygen is used as an oxidant, and other oxidants are not needed. All the raw materials of the catalyst are rich in resource and low in price, and the catalyst can be recycled without inactivation and is very stable to air, water and heat.

Facile synthesis of polysubstituted cyclopropanes using α-tosyloxyketones

A facile synthesis of polysubstituted cyclopropanes (5) by the treatment of pyridinium ylides, generated in situ from pyridinium toslyates (2), with arylidenemalonitrile (4) is presented. Pyridinium toslyates (2) were obtained by reacting α-tosyloxyketone

Metal-free C(sp3)-H bond sulfonyloxylation of 2-alkylpyridines and alkylnitrones

Pyridin-2-ylmethyl tosylate derivatives are obtained in high yields from 2-alkylpyridine 1-oxides via a [3,3]-sigmatropic rearrangement of the adduct between 2-alkylpridine 1-oxides with benzenesulfonyl chlorides. Moreover, alkylnitrones also undergo [3,3]-sigmatropic rearrangement to give α-tosylated ketones after hydrolysis. Substitution reactions with nucleophiles then lead to diverse useful functionalizations for the synthesis of pincer ligands.

α-tosyloxyketones as versatile synthetic equivalents to α-Haloketones: Facile synthesis of disubstituted oxazoles

A facile synthesis of disubstituted oxazoles (3) in good yields via decarboxylative oxidative cyclization of primary amino acids (1) and α-tosyloxyketones (2) is described.

A convenient [hydroxy(tosyloxy)iodo]benzene-mediated one-pot synthesis of 2-arylimidazo[2,1-b[benzothiazoles

Several 2-arylimidazo[2,1-b]benzothiazoles (4) have been conveniently synthesized in one-pot reactions via α-tosyloxylation of enolizable ketones (1) using [hydroxy(tosyloxy)iodo]benzene 2 in acetonitrile, followed by treatment with 2-amino-6-(substituted

Oxidative breakdown of iodoalkanes to catalytically active iodine species: A case study in the α-tosyloxylation of ketones

Catalysis of the oxidative processes by iodoarenes has become a promising direction in synthesis. The mechanism, involving the well-known isolable hypervalent iodine species, is generally limited to aromatic iodides, since the corresponding aliphatic spec

Novel α-tosyloxylation of ketones catalyzed by the in situ generated hypoiodous acid from alkyl iodide

Using a catalytic amount of 1-iodopropane, a novel and efficient procedure has been developed for direct preparation of α-tosyloxyketones from ketones. In this protocol, 1-iodopropane is first oxidized into iodosylpropane, which decomposes to form the key

2,4,6-Tris(4-iodophenoxy)-1,3,5-triazine as a new recyclable "iodoarene" for in situ generation of hypervalent iodine(III) reagent for α-tosyloxylation of enolizable ketones

The synthesis of 2,4,6-tris[(4-iodo)phenoxy)]-1,3,5-triazine 6, as a new recyclable nonpolymeric analogue of iodobenzene is achieved using the reaction of 2,4,6-trichloro-1,3,5-triazine with 4-iodophenol in the presence of KOH. The application of 6 as a r

Effective α-tosyloxylation of ketones using 1,1,1-trifluoro-2-iodoethane as catalyst

With 1,1,1-trifluoro-2-iodoethane as catalyst, a novel and efficient procedure has been developed for preparation of α-tosyloxyketones from ketones. In this protocol, 1,1,1-trifluoro-2-iodoethane is first oxidized by m-chloroperbenzoic acid to a hypervale