212519-38-5

Basic information

• Product Name: 9-methyl-7-(4-methylphenyl)-11H-[1,3]oxazino[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]cinnolin-11-one
• Synonyms: 9-methyl-7-(4-methylphenyl)-11H-[1,3]oxazino[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]cinnolin-11-one
• CAS NO: 212519-38-5
• Molecular Formula: C₂₃H₁₄N₄O₂S
• Molecular Weight: 410.44786
• Mol File: 212519-38-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9-methyl-7-(4-methylphenyl)-11H-[1,3]oxazino[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]cinnolin-11-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-methyl-7-(4-methylphenyl)-11H-[1,3]oxazino[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]cinnolin-11-one(212519-38-5)
• EPA Substance Registry System: 9-methyl-7-(4-methylphenyl)-11H-[1,3]oxazino[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]cinnolin-11-one(212519-38-5)

Safety Data

• Hazardous Substances Data: 212519-38-5(Hazardous Substances Data)

Upstream product

• 212520-21-3 (3-Cyano-4-p-tolyl-pyrido[3,2-c]cinnolin-2-ylsulfanyl)-acetic acid ethyl ester 
• 212520-45-1 8-Amino-7-p-tolyl-10-thia-5,6,11-triaza-cyclopenta[b]phenanthrene-9-carboxylic acid ethyl ester 
• 212519-28-3 3-cyano-4-(p-tolyl)pyrido[3,2-c]cinnolin-2(1H)-thione 
• 212519-24-9 AN-848/40633652 
• 306-18-3 2-phenylhydrazonomalononitrile 
• 108-88-3 toluene 
• 91913-27-8 (4-aminocinnolin-3-yl)-p-tolylmethanone 
• 108-24-7 acetic anhydride 
• 212519-34-1 8-Amino-7-p-tolyl-10-thia-5,6,11-triaza-cyclopenta[b]phenanthrene-9-carboxylic acid 

Downstream Products

• 212519-54-5 11-Chloro-9-methyl-7-p-tolyl-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthrene 
• 212519-58-9 (9-Methyl-7-p-tolyl-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthren-11-yl)-hydrazine 
• 212519-74-9 5-methyl-7-(p-tolyl)-1,2,4-triazolo[4''',3''':1'',6'']pyrimido[4'',5'':4',5']thieno[3',2':5,6]pyrido[3,2-c]-cinnolin-3(2H)-thione 
• 212519-49-8 9-Methyl-7-p-tolyl-10H-12-thia-5,6,8,10,13-pentaaza-indeno[1,2-b]phenanthren-11-one 

Relevant articles and documents

New heterocycles from thienopyridocinnolines

3-Cyano-4-(p-tolyl)pyrido[3,2-c]cinnolin-2(1H) thione 3 was reacted with α-halo ketones, esters, or amides to give the intermediates, S-alkylated products 5b-h, respectively, which underwent intramolecular ring closure reactions with ethanolic sodium ethoxide to give thienopyridocinnolines 6a- h. Pyrimidothienopyridocinnolines 9 and 11 were obtained by treatment of oxazino compound 8 with hydrazine hydrate and ammonium acetate. Treatment of hydrazino derivative 13 with acetylacetone, triethylorthoformate, carbon disulphide, ethyl chloroformate, and acetic anhydride afforded triazolopyrimidothienopyridocinnolines 14-16, 18, and 21, while with nitrous acid the corresponding tetrazolo compound 19 was produced. 3-Cyano-4-(p-tolyl)pyrido[3,2-c]cinnolin-2(1H) thione 3 was reacted with α-halo ketones, esters, or amides to give the intermediates, S-alkylated products 5b-h, respectively, which underwent intramolecular ring closure reactions with ethanolic sodium ethoxide to give thienopyridocinnolines 6a-h. Pyrimidothienopyridocinnolines 9 and 11 were obtained by treatment of oxazino compound 8 with hydrazine hydrate and ammonium acetate. Treatment of hydrazino derivative 13 with acetylacetone, triethylorthoformate, carbon disulphide, ethyl chloroformate, and acetic anhydride afforded triazolopyrimidothienopyridocinnolines 14-16,18, and 21, while with nitrous acid the corresponding tetrazolo compound 19 was produced.