cas 212776-19-7, trans 4-DiMethylaMinocrotonic Acid Methyl Ester | Articles data ｜lookchem

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212776-19-7

Articles about 212776-19-7Total 4 be found

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Chlorobenzene-pyridine compounds and application thereof
The invention relates to chlorobenzene-pyridine compounds and an application thereof. The compounds can be used for preparing a Smoothened protein inhibitor and a drug for resisting adenocarcinoma andesophagus cancer and have the structure in the general formula (I) shown in the description, wherein X is selected from the structure shown in the description, R1 is selected from H or the structureshown in the description, and R2 is selected from the structure shown in the description.
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Paragraph 0112; 0120; 0121; 0122

(2018/04/01)

PYRAZOLYLAMINOPURINES AS ITK INHIBITORS
Provided are pyrazolylaminopurine compounds that are inhibitors of ITK kinase, compositions containing these compounds and methods for treating diseases mediated by ITK kinase. In particular, provided are compounds of Formula I or II, stereoisomers, tauto
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Page/Page column 92; 93

(2016/11/07)

IDO INHIBITORS
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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Paragraph 2179

(2016/10/27)

Antineoplastic combinations
This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms.
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(2008/06/13)

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Chemical Properties

Boiling Point: 176℃
Flash Point:63℃
Density: 0.964
Solubility:Dichloromethane, Methanol
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
PKA: 7.61±0.28(Predicted)
PSA: 29.54000
LogP: 0.27720

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