212776-19-7Relevant academic research and scientific papers
Chlorobenzene-pyridine compounds and application thereof
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Paragraph 0112; 0120; 0121; 0122, (2018/04/01)
The invention relates to chlorobenzene-pyridine compounds and an application thereof. The compounds can be used for preparing a Smoothened protein inhibitor and a drug for resisting adenocarcinoma andesophagus cancer and have the structure in the general formula (I) shown in the description, wherein X is selected from the structure shown in the description, R1 is selected from H or the structureshown in the description, and R2 is selected from the structure shown in the description.
PYRAZOLYLAMINOPURINES AS ITK INHIBITORS
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Page/Page column 92; 93, (2016/11/07)
Provided are pyrazolylaminopurine compounds that are inhibitors of ITK kinase, compositions containing these compounds and methods for treating diseases mediated by ITK kinase. In particular, provided are compounds of Formula I or II, stereoisomers, tauto
IDO INHIBITORS
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Paragraph 2179, (2016/10/27)
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
Antineoplastic combinations
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, (2008/06/13)
This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms.
