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D-(-)-2-Chlorophenylglycine methyl ester HCL is a chemical compound that serves as an ester of the amino acid 2-chlorophenylglycine, commonly found in hydrochloride salt form. It is a significant intermediate in pharmaceutical research and development, known for its potential therapeutic properties in treating mental health disorders and as a building block in the synthesis of various pharmaceutical drugs.

212838-70-5

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  • Benzeneacetic acid, a-amino-2-chloro-, methyl ester,hydrochloride (1:1), (aR)-

    Cas No: 212838-70-5

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212838-70-5 Usage

Uses

Used in Pharmaceutical Research and Development:
D-(-)-2-Chlorophenylglycine methyl ester HCL is used as a research compound for its potential therapeutic properties, particularly in the treatment of schizophrenia, anxiety disorders, and other mental health conditions. Its unique structure allows it to be a valuable tool for scientists and researchers in exploring new avenues for medication development.
Used in Medication Production:
As an important intermediate, D-(-)-2-Chlorophenylglycine methyl ester HCL is used in the synthesis of various pharmaceutical drugs. Its role in the production process is crucial for creating medications that address a range of health issues, making it a vital component in the pharmaceutical industry's efforts to develop new and effective treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 212838-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,8,3 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 212838-70:
(8*2)+(7*1)+(6*2)+(5*8)+(4*3)+(3*8)+(2*7)+(1*0)=125
125 % 10 = 5
So 212838-70-5 is a valid CAS Registry Number.

212838-70-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name D-(-)-2-CHLOROPHENYLGLYCINE METHYL ESTER HCL

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:212838-70-5 SDS

212838-70-5Relevant articles and documents

Isotopically Directed Symmetry Breaking and Enantioenrichment in Attrition-Enhanced Deracemization

Blackmond, Donna G.,Houk, K. N.,Murray, James I.,Richardson, Paul F.,Sanders, Jacob N.

supporting information, (2020/03/10)

The evolution of homochirality via attrition-enhanced deracemization (AED) of enantiomorphic solids is carried out using molecules that differ only in the isotopic composition of a phenyl group positioned remote from the chiral center. Enantioenrichment c

Preparation method of (S)-chlorophenylglycine methyl ester hydrochloride

-

Paragraph 0005; 0006; 0007; 0008, (2017/08/29)

The invention discloses a preparation method of (S)-chlorophenylglycine methyl ester hydrochloride. The preparation method comprises the following steps: 1) adding a mixture of o-chlorobenzaldehyde and trimethylsilyl cyanide into a reaction flask, then ad

Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach

Zhan, Peng,Chen, Wenmin,Li, Zhenyu,Li, Xiao,Chen, Xuwang,Tian, Ye,Pannecouque, Christophe,Clercq, Erik De,Liu, Xinyong

, p. 6795 - 6802 (2013/01/15)

The present work is an extension of our ongoing efforts towards the development and identification of new molecules with anti-HIV activity which have previously led to the discovery of arylazolylthioacetanilides as highly active NNRTIs. In this article, a series of 2-2-(3-(2-chlorophenyl)pyrazin-2- ylthio)-N-arylacetamide derivatives were synthesized and evaluated for in vitro anti-HIV activity. Most of the tested compounds exhibited moderate activities against wild-type HIV-1. Among them, compound 6k showed significant activity against wild-type HIV-1 with an EC50 value of 1.7 μM, along with moderate activity against wild-type reverse transcriptase (RT). The preliminary structure-activity relationship (SAR) and docking calculations of this new series of compounds were also investigated, which may help designing more potent molecules.

Method for preparing 2-thienylethylamine derivatives

-

, (2008/06/13)

PCT No. PCT/FR98/00441 Sec. 371 Date Sep. 2, 1999 Sec. 102(e) Date Sep. 2, 1999 PCT Filed Mar. 5, 1998 PCT Pub. No. WO98/39322 PCT Pub. Date Sep. 11, 1998The present invention relates to a process for the preparation of 2-thienylethylamine derivatives of general formula: as well as their acid addition salts, in which R represents a halogen atom and R1 represents a C1-C4 alkyl group, characterized in that a thienylglycidic derivative of general formula: in which M represents an alkali metal atom or a fraction of an alkaline-earth metal atom, is reacted with a phenylglycine ester, optionally in the form of a strong acid salt, of general formula: in which R and R1 have the same meaning as above, in the presence of an alkali metal borchydride of general formula: X-YIV in which X represents an alkali metal atom and Y represents a group of formula: -BH3CN or -BH(4-w)Zw in which Z represents a carboxylic acid residue and optionally in the presence of a C1-C4 carboxylic acid, which gives the desired compound in the form of a free base which can be treated, if necessary, with an acid in order to obtain an addition salt of this compound.

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