214273-18-4Relevant articles and documents
Prophylactic or therapeutic agent for diseases attributable to infection with helicobacters
-
, (2008/06/13)
The present invention relates to an agent for the prophylaxis and treatment of diseases caused by Helicobacter infections, which comprises (S)-1-cyclopropyl-1,4-dihydro-7-[2-(N,N-dimethylaminomethyl)morpholino]-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxyl
Synthesis of 2-substituted morpholines from dihydroxyalkylsulfamates
Bulatov,Ermakov,Tartakovsky
, p. 2100 - 2102 (2007/10/03)
2-Substituted morpholines and hexahydro-1,4-oxazepines were prepared by cyclodehydration of potassium dihydroxyalkylsulfamates in concentrated sulfuric acid.
Synthesis and structure-activity relationships of 7-(2- aminoalkyl)morpholinoquinolones as anti-helicobacter pylori agents
Sakurai, Nobuhiro,Sano, Mitsuharu,Hirayama, Fumihiro,Kuroda, Tsuyoshi,Uemori, Satoru,Moriguchi, Akihiko,Yamamoto, Katsuhiro,Ikeda, Yoshifumi,Kawakita, Takeshi
, p. 2185 - 2190 (2007/10/03)
A series of the titled compounds was synthesized and tested for anti- Helicobacter pylori activities. We discovered Y-34867 having the most potent activity against Helicobacter pylori among the quinolones tested along with high photostability. Furthermore