2-Morpholinemethanamine,N,N-dimethyl-,(2S)-(9CI)

Base Information

• Chemical Name: 2-Morpholinemethanamine,N,N-dimethyl-,(2S)-(9CI)
• CAS No.: 214273-18-4
• Molecular Formula: C₇H₁₆N₂O
• Molecular Weight: 144.217
• Hs Code.: 2934999090
• Mol file: 214273-18-4.mol

Synonyms:(S)-N,N-Dimethyl-2-morpholinemethanamine

Chemical Property of 2-Morpholinemethanamine,N,N-dimethyl-,(2S)-(9CI)

Chemical Property:

• PSA: 24.50000
• LogP: -0.13480

Purity/Quality:

97% ^*data from raw suppliers

(S)-N,N-Dimethyl-2-morpholinemethanamine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Morpholinemethanamine,N,N-dimethyl-,(2S)-(9CI)

There total 7 articles about 2-Morpholinemethanamine,N,N-dimethyl-,(2S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H17N2O5S(1-)*K(1+) → N,N-dimethyl(morpholin-2-yl)methanamine (122894-56-8,214273-18-4)

Guidance literature:

With sulfuric acid; In methanol; at 150 ℃; for 3h;

DOI:10.1007/BF02494855

Reference yield:

potassium N-(3-chloro-2-hydroxypropyl)-N-(2-hydroxyethyl)sulfamate → N,N-dimethyl(morpholin-2-yl)methanamine (122894-56-8,214273-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / H₂O / 48 h / 20 °C

2: H₂SO₄ / methanol / 3 h / 150 °C

With potassium hydroxide; sulfuric acid; In methanol; water; 1: Substitution / 2: Elimination;

DOI:10.1007/BF02494855

Reference yield:

(S)-4-benzyl-2-(N,N-dimethylaminomethyl)morpholine (122894-38-6) → (R)-N,N-dimethyl-1-(morpholin-2-yl)methanamine (214273-19-5,214273-18-4)

Guidance literature:

With hydrazine hydrate; palladium-carbon; In ethanol;

upstream raw materials:

formaldehyd

[(2R)-4-benzylmorpholin-2-yl]methanamine

(4-benzylmorpholin-2-yl)methanamine

(S)-(4-benzylmorpholin-2-yl)methanamine

Downstream raw materials:

(S)-1-cyclopropyl-1,4-dihydro-7-[2-(N,N-dimethylaminomethyl)morpholino]-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid