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2,4,6-Trimethylpiperidine is a chemical compound belonging to the piperidine class, characterized by its clear, colorless liquid form and a distinct pungent odor. It serves as a versatile building block in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.

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  • 21974-48-1 Structure
  • Basic information

    1. Product Name: 2,4,6-trimethylpiperidine
    2. Synonyms: 2,4,6-trimethylpiperidine;Einecs 244-690-3
    3. CAS NO:21974-48-1
    4. Molecular Formula: C8H17N
    5. Molecular Weight: 127.22728
    6. EINECS: 244-690-3
    7. Product Categories: N/A
    8. Mol File: 21974-48-1.mol
  • Chemical Properties

    1. Melting Point: -1°C (estimate)
    2. Boiling Point: 156.06°C (estimate)
    3. Flash Point: 38°C
    4. Appearance: /
    5. Density: 0.8315
    6. Vapor Pressure: 1.87mmHg at 25°C
    7. Refractive Index: 1.4412
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,4,6-trimethylpiperidine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,4,6-trimethylpiperidine(21974-48-1)
    12. EPA Substance Registry System: 2,4,6-trimethylpiperidine(21974-48-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21974-48-1(Hazardous Substances Data)

21974-48-1 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,4,6-Trimethylpiperidine is used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to form complex molecular structures that contribute to the development of new drugs and pesticides.
Used as a Corrosion Inhibitor:
In the industrial sector, 2,4,6-trimethylpiperidine is employed as a corrosion inhibitor to protect metal surfaces from degradation, extending the lifespan of equipment and reducing maintenance costs.
Used as a Solvent in Industrial Applications:
2,4,6-Trimethylpiperidine also serves as a solvent in various industrial processes due to its ability to dissolve a wide range of substances, facilitating chemical reactions and improving process efficiency.
Safety Precautions:
Given its potential health hazards, including skin and eye irritation, 2,4,6-trimethylpiperidine should be handled with care in a well-ventilated area to minimize exposure risks. Proper safety measures and personal protective equipment are essential when working with this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 21974-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,7 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21974-48:
(7*2)+(6*1)+(5*9)+(4*7)+(3*4)+(2*4)+(1*8)=121
121 % 10 = 1
So 21974-48-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H17N/c1-6-4-7(2)9-8(3)5-6/h6-9H,4-5H2,1-3H3

21974-48-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4,6-trimethylpiperidine

1.2 Other means of identification

Product number -
Other names Piperidine,2,4,6-trimethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21974-48-1 SDS

21974-48-1Relevant articles and documents

Titanium(III)-Oxo Clusters in a Metal-Organic Framework Support Single-Site Co(II)-Hydride Catalysts for Arene Hydrogenation

Ji, Pengfei,Song, Yang,Drake, Tasha,Veroneau, Samuel S.,Lin, Zekai,Pan, Xiandao,Lin, Wenbin

, p. 433 - 440 (2018/01/17)

Titania (TiO2) is widely used in the chemical industry as an efficacious catalyst support, benefiting from its unique strong metal-support interaction. Many proposals have been made to rationalize this effect at the macroscopic level, yet the underlying molecular mechanism is not understood due to the presence of multiple catalytic species on the TiO2 surface. This challenge can be addressed with metal-organic frameworks (MOFs) featuring well-defined metal oxo/hydroxo clusters for supporting single-site catalysts. Herein we report that the Ti8(μ2-O)8(μ2-OH)4 node of the Ti-BDC MOF (MIL-125) provides a single-site model of the classical TiO2 support to enable CoII-hydride-catalyzed arene hydrogenation. The catalytic activity of the supported CoII-hydride is strongly dependent on the reduction of the Ti-oxo cluster, definitively proving the pivotal role of TiIII in the performance of the supported catalyst. This work thus provides a molecularly precise model of Ti-oxo clusters for understating the strong metal-support interaction of TiO2-supported heterogeneous catalysts.

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