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(S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide is a complex organic compound with a unique structure that features a sulfinamide group, a propanesulfinate, a phenyl(methyl)dicyclohexylphosphane, and a 3,5-di-tert-butyl-4-methoxyphenyl group. The stereochemistry indicated by the (S)and (R)prefixes is crucial for its properties and potential applications. (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide holds promise in various fields, including pharmaceuticals, materials science, and organic chemistry research, particularly as a chiral ligand in asymmetric synthesis.

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  • N-[(S)-(3,5-Ditert-butyl-4-methoxyphenyl)-(2-dicyclohexylphosphanylphenyl)methyl]-N,2-dimethylpropane-2-sulfinamide;2241598-34-3

    Cas No: 2241598-34-3

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  • Amadis Chemical Co., Ltd.
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  • 2241598-34-3 Structure
  • Basic information

    1. Product Name: (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide
    2. Synonyms:
    3. CAS NO:2241598-34-3
    4. Molecular Formula:
    5. Molecular Weight: 639.967
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2241598-34-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 702.9±70.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide(2241598-34-3)
    11. EPA Substance Registry System: (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide(2241598-34-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2241598-34-3(Hazardous Substances Data)

2241598-34-3 Usage

Uses

Used in Pharmaceutical Industry:
(S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide is used as a chiral ligand for asymmetric synthesis, which is crucial in the development of enantiomerically pure drugs. (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide's unique structural features allow for the creation of pharmaceuticals with improved efficacy and reduced side effects.
Used in Materials Science:
In the field of materials science, (S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide can be utilized in the development of novel materials with specific properties, such as improved stability or reactivity, due to its unique molecular structure.
Used in Organic Chemistry Research:
(S)-N-((R)-(3,5-di-tert-butyl-4-methoxyphenyl)(2-(dicyclohexylphosphanyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide serves as a valuable compound in organic chemistry research, where it can be employed in the synthesis of complex organic molecules and the study of reaction mechanisms, further expanding the understanding of organic chemistry and its applications.

Check Digit Verification of cas no

The CAS Registry Mumber 2241598-34-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,2,4,1,5,9 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2241598-34:
(9*2)+(8*2)+(7*4)+(6*1)+(5*5)+(4*9)+(3*8)+(2*3)+(1*4)=163
163 % 10 = 3
So 2241598-34-3 is a valid CAS Registry Number.

2241598-34-3Downstream Products

2241598-34-3Relevant articles and documents

Sequential Pd0- and PdII-Catalyzed Cyclizations: Enantioselective Heck and Nucleopalladation Reactions

Arora, Ramon,Bajohr, Jonathan,Lautens, Mark,Torelli, Alexa,Whyte, Andrew

, p. 20231 - 20236 (2021/08/13)

An enantioselective consecutive cyclization/coupling process, catalyzed by palladium is reported. Stereoinduction arises from an enantioselective carbopalladation, generating an intermediate which promotes a nucleopalladation step. The dual cyclization se

Sulfonamide type chiral monophosphine ligand as well as preparation method and application thereof

-

Paragraph 0045-0046; 0067-0068, (2018/12/14)

The invention discloses a sulfonamide type chiral monophosphine ligand. The chiral monophosphine ligand is a compound shown as a formula I in the description. The invention also discloses a syntheticmethod of the ligand. The method comprises the following

Palladium-Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3,3-Disubstituted 2,3-Dihydrobenzofuran

Zhang, Zhan-Ming,Xu, Bing,Qian, Yanyan,Wu, Lizuo,Wu, Yuanqi,Zhou, Lujia,Liu, Yu,Zhang, Junliang

supporting information, p. 10373 - 10377 (2018/07/31)

The first example of highly enantioselective intramolecular hydroarylation of allyl aryl ethers was realized by palladium-catalyzed reductive heck reactions utilizing a new chiral sulfinamide phosphine ligand (N-Me-XuPhos). N-Me-XuPhos can be easily prepared on gram scale from readily available starting materials in a one-pot synthesis approach. A series of optically active 2,3-dihydrobenzofurans bearing a quaternary stereocenter were obtained in good yields and with excellent enantioselectivities. The practicality of this reaction was validated in the straightforward synthesis of CB2 receptor agonists. Moreover, deuterium was efficiently incorporated into the products.

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