22439-58-3Relevant articles and documents
Synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene tethered imidazo[1,2-a]pyridine-3-carboxamides
Pulipati, Lokesh,Sridevi, Jonnalagadda Padma,Yogeeswari, Perumal,Sriram, Dharmarajan,Kantevari, Srinivas
, p. 3135 - 3140 (2016)
A series of novel dibenzo[b,d]thiophene tethered imidazo[1,2-a]pyridine carboxamides 7a-s were designed and synthesized. The required building block, 2-dibenzo[b,d]thiophenyl imidazo[1,2-a]pyridine carboxylic acid (5) was synthesized from commercial dibenzo[b,d]thiophene in good yields following five-step reaction sequence. The desired carboxamides 7a-s was prepared through coupling of acid 5 with various benzyl amines. All the new analogues 7a-s was characterized by their NMR and mass spectral analysis. Among nineteen new compounds 7a-s screened for in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv, three compounds 7k (MIC: 0.78 μg/mL); 7e and 7n (MIC: 1.56 μg/mL) were identified as potent analogues with low cytotoxicity. The results reported here will help global efforts for identification of potential lead antimycobacterial agents.
Click-based synthesis and antitubercular evaluation of novel dibenzo[b,d]thiophene-1,2,3-triazoles with piperidine, piperazine, morpholine and thiomorpholine appendages
Pulipati, Lokesh,Yogeeswari, Perumal,Sriram, Dharmarajan,Kantevari, Srinivas
, p. 2649 - 2654 (2016)
A series of novel piperidine, piperazine, morpholine and thiomorpholine appended dibenzo[b,d]thiophene-1,2,3-triazoles were designed and synthesized utilizing azide-alkyne click chemistry in the penultimate step. The required azide building block 6a-e was
A luminescent Eu(III) complex based on 2-(4′, 4′, 4′-trifluoro-1′, 3′-dioxobutyl)-dibenzothiophene for light-emitting diodes
Liu, Sheng-Gui,Gong, Meng-Lian,Wang, Sheng,Tan, Xiu-Mei
, p. 731 - 734 (2009)
Complex Eu(dbt)3(phen) (Hdbt = 2-(4′, 4′, 4′-trifluoro-1′, 3′-dioxobutyl)-dibenzothiophene, phen = 1,10-phenanthroline) was synthesized. The complex emits red luminescence, characteristic of the 5D0 → 7FJ (J = 0-4) emission bands of Eu3+ under near ultraviolet. A red conversion light-emitting diode (LED) device was fabricated by coating complex onto InGaN-based-LED chip that emits 395 nm ultraviolet light. When the mass ratio of the red phosphor to the silicone is 1:25, the LED device's CIE chromaticity coordinates are x = 0.5835, y = 0.2857, and the luminescence efficiency is 1.29 lm/w. All the results show that this europium complex may act as a red component in fabrication of white LEDs with high color-rendering index.
Diaryl ring fused sulfides and diaryl ring fused selenides, and synthesis method and application thereof
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Paragraph 0077; 0078; 0079; 0080, (2017/06/20)
The invention discloses a synthesis method of diaryl ring fused sulfides represented by formula (B) and diaryl ring fused selenides represented by formula (C). The method is characterized in that a reaction of a reaction raw material high-iodine salt is carried out in dimethyl sulfoxide under the action of an inorganic sulfuration reagent or selenylation reagent and an alkali at 60-100 DEG C to obtain the diaryl ring fused sulfides and the diaryl ring fused selenides. Sulfur or selenium is introduced in the later stage in the presence of a nonmetal catalyst, so poisoning of sulfur to a metal catalyst in the early stage reaction is avoided; the above inorganic sulfur source is nontoxic and odorless; and two aryl groups in the high-iodine salt are fully used, so the atom economy and the greenness of the method are fully shown. The diaryl ring fused sulfides and the diaryl ring fused selenides prepared through the method can be applied to synthesize photoelectric materials BTBT and BTBS.
Transition-Metal-Free Diarylannulated Sulfide and Selenide Construction via Radical/Anion-Mediated Sulfur-Iodine and Selenium-Iodine Exchange
Wang, Ming,Fan, Qiaoling,Jiang, Xuefeng
supporting information, p. 5756 - 5759 (2016/11/17)
A facile, straightforward protocol was established for diarylannulated sulfide and selenide construction through S-I and Se-I exchange without transition metal assistance. Elemental sulfur and selenium served as the chalcogen source. Diarylannulated sulfides were systematically achieved from a five- to eight-membered ring. A trisulfur radical anion was demonstrated as the initiator for this radical process via electron paramagnetic resonance (EPR) study. OFET molecules [1]benzothieno[3,2-b][1]benzothiophene (BTBT) and [1]benzothieno[3,2-b][1]benzoselenophene (BTBS) were efficiently established.
A simple and efficient synthesis of dibenzothiophene via BF 3·OEt2-promoted intramolecular annulation
Shang, Xiaobo,Chen, Wanzhi,Yao, Yingming
, p. 851 - 854 (2013/05/23)
A simple and efficient protocol promoted by BF3·OEt 2 for synthesizing functionalized dibenzothiophenes (DBTs) has been demonstrated. The annulation condition can tolerate a variety of functional groups. Georg Thieme Verlag Stuttgart · New York.
Design, synthesis, and structure-activity correlations of novel dibenzo[b,d furan, dibenzo[b,d]thiophene, and N-methylcarbazole clubbed 1,2,3-triazoles as potent inhibitors of mycobacterium tuberculosis
Patpi, Santhosh Reddy,Pulipati, Lokesh,Yogeeswari, Perumal,Sriram, Dharmarajan,Jain, Nishant,Sridhar, Balasubramanian,Murthy, Ramalinga,Anjana Devi,Kalivendi, Shasi Vardhan,Kantevari, Srinivas
experimental part, p. 3911 - 3922 (2012/07/14)
A molecular hybridization approach is an emerging structural modification tool to design new molecules with improved pharmacophoric properties. In this study, 1,2,3-triazole-based Mycobacterium tuberculosis inhibitors and synthetic and natural product-bas
Efficient synthesis of unsymmetrical dibenzothiophenes by acid-mediated intramolecular cyclization of biaryl methyl sulfoxides
Pandya, Vrajesh B.,Jain, Mukul R.,Chaugule, Balaji V.,Patel, Jigar S.,Parmar, Bhavesh M.,Joshi, Jignesh K.,Patel, Pankaj R.
, p. 497 - 505 (2011/11/29)
Aconvenient and high-yielding synthesis of unsymmetrical dibenzothiophenes has been achieved by an acid-mediated ring closure of the biphenyl ring having a sulfoxide substituent at the ortho position. Various functional groups are well tolerated in this methodology. Taylor & Francis Group, LLC.
SCHWEFELVERBINDUNGEN DES ERDOELS XVI. DIBENZOTHIOPHENE MIT EINEM UNVERZWEIGTEN C1-C5-ALKYLREST
Boberg, Friedrich,Bruns, Wolfgang,Musshoff, Dagmar
, p. 13 - 32 (2007/10/02)
The preparation of all position isomers of dibenzothiophenes with a linear C1-C5-side chain and of the corresponding 5,5-dioxides is described. (1)H-NMR data and GC-purities are given. Key words: Monoalkyldibenzothiophenes; methyldibenzothiophenes; ethyldibenzothiophenes; propyldibenzothiophenes; butyldibenzothiophenes; pentyldibenzothiophenes; monoalkyldibenzothiophene-5,5-dioxides.
