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4-Hydroxy-1-piperidineethanol 96, also known as 4-Hydroxy-1-(2-hydroxyethyl)piperidine, is a white crystalline solid with a molecular formula of C6H13NO2. It is a chemical compound that serves as a building block in the synthesis of pharmaceuticals and other organic compounds. Known for its ability to act as a chiral auxiliary in asymmetric synthesis, it is a valuable tool for producing enantiomerically pure molecules. 4-HYDROXY-1-PIPERIDINEETHANOL 96 is also used in the production of various drugs and medicinal products, as well as in the development of new synthetic methodologies. Overall, 4-Hydroxy-1-piperidineethanol 96 plays a significant role in the chemical and pharmaceutical industries as a versatile and essential intermediate.

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  • 224431-84-9 Structure
  • Basic information

    1. Product Name: 4-HYDROXY-1-PIPERIDINEETHANOL 96
    2. Synonyms: 4-HYDROXY-1-PIPERIDINEETHANOL 96;1-Piperidineethanol, 4-hydroxy- (9CI);1-(2-Hydroxyethyl)-4-hydroxypiperidine
    3. CAS NO:224431-84-9
    4. Molecular Formula: C7H15NO2
    5. Molecular Weight: 145.1995
    6. EINECS: N/A
    7. Product Categories: ALCOHOL;AMINETERTIARY;API intermediates
    8. Mol File: 224431-84-9.mol
  • Chemical Properties

    1. Melting Point: 33-40 °C
    2. Boiling Point: N/A
    3. Flash Point: >230 °F
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-HYDROXY-1-PIPERIDINEETHANOL 96(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-HYDROXY-1-PIPERIDINEETHANOL 96(224431-84-9)
    11. EPA Substance Registry System: 4-HYDROXY-1-PIPERIDINEETHANOL 96(224431-84-9)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 2
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 224431-84-9(Hazardous Substances Data)

224431-84-9 Usage

Uses

Used in Pharmaceutical Industry:
4-Hydroxy-1-piperidineethanol 96 is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its role in creating enantiomerically pure molecules makes it a crucial component in the development of high-quality drugs and medicinal products.
Used in Asymmetric Synthesis:
4-Hydroxy-1-piperidineethanol 96 is used as a chiral auxiliary in asymmetric synthesis. This application is vital for producing molecules with specific stereochemistry, which is essential for the effectiveness, safety, and selectivity of pharmaceutical compounds.
Used in Chemical Industry:
4-Hydroxy-1-piperidineethanol 96 is utilized in the development of new synthetic methodologies. Its versatility as an intermediate allows for the creation of innovative chemical processes and the synthesis of a wide range of organic compounds.
Used in Research and Development:
4-Hydroxy-1-piperidineethanol 96 is employed in research and development for its potential applications in various fields. Its unique properties and reactivity make it an interesting subject for scientific exploration and the advancement of chemical knowledge.

Check Digit Verification of cas no

The CAS Registry Mumber 224431-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,4,4,3 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 224431-84:
(8*2)+(7*2)+(6*4)+(5*4)+(4*3)+(3*1)+(2*8)+(1*4)=109
109 % 10 = 9
So 224431-84-9 is a valid CAS Registry Number.

224431-84-9 Well-known Company Product Price

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  • Aldrich

  • (655732)  4-Hydroxy-1-piperidineethanol  96%

  • 224431-84-9

  • 655732-1G

  • 526.50CNY

  • Detail
  • Aldrich

  • (655732)  4-Hydroxy-1-piperidineethanol  96%

  • 224431-84-9

  • 655732-5G

  • 1,805.31CNY

  • Detail

224431-84-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-hydroxyethyl)piperidin-4-ol

1.2 Other means of identification

Product number -
Other names 1-(2-Hydroxyethyl)-4-hydroxypiperidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:224431-84-9 SDS

224431-84-9Downstream Products

224431-84-9Relevant articles and documents

CHEMOKINE RECEPTOR ANTAGONISTS

-

Page/Page column 27; 37, (2010/02/13)

A compound of formula (I) or a pharmaceutically acceptable salt or prodrug ester thereof, wherein the variants R, R9, Z, X, Q and Y are defined in the specification.

Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains

Blizzard, Timothy A.,DiNinno, Frank,Morgan II, Jerry D.,Wu, Jane Y.,Chen, Helen Y.,Kim, Seongkon,Chan, Wanda,Birzin, Elizabeth T.,Yang, Yi Tien,Pai, Lee-Yuh,Zhang, Zhoupeng,Hayes, Edward C.,DaSilva, Carolyn A.,Tang, Wei,Rohrer, Susan P.,Schaeffer, James M.,Hammond, Milton L.

, p. 3865 - 3868 (2007/10/03)

A series of benzoxathiin SERAMs with heteroatom-substituted amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue.

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