4-Hydroxy-1-piperidineethanol

Base Information

Chemical Name:4-Hydroxy-1-piperidineethanol
CAS No.:224431-84-9
Molecular Formula:C7H15 N O2
Molecular Weight:145.202
Hs Code.:
European Community (EC) Number:624-894-2
DSSTox Substance ID:DTXSID70564189
Wikidata:Q82448799
Mol file:224431-84-9.mol

Synonyms:4-Hydroxy-1-piperidineethanol;224431-84-9;1-(2-HYDROXYETHYL)PIPERIDIN-4-OL;4-HYDROXY-1-PIPERIDINEETHANOL 96;1-(2-Hydroxy-ethyl)-piperidin-4-ol;SCHEMBL916463;4-hydroxy-1-piperidine-ethanol;DTXSID70564189;DOILPQLHDAWKCZ-UHFFFAOYSA-N;4-Hydroxy-1-piperidineethanol, 96%;AKOS009094460;MB05042;AS-76108;D93319;J-014721

Suppliers and Price of 4-Hydroxy-1-piperidineethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-Hydroxy-1-piperidineethanol 96%
5g
$ 140.00

Sigma-Aldrich
4-Hydroxy-1-piperidineethanol 96%
1g
$ 51.20

American Custom Chemicals Corporation
4-HYDROXY-1-PIPERIDINEETHANOL 95.00%
5G
$ 934.43

American Custom Chemicals Corporation
4-HYDROXY-1-PIPERIDINEETHANOL 95.00%
1G
$ 648.70

Total 8 raw suppliers

Chemical Property of 4-Hydroxy-1-piperidineethanol

Chemical Property:

Melting Point:33-40 °C
Flash Point:>230 °F
PSA：43.70000
LogP:-0.62670
XLogP3:-0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:145.110278721
Heavy Atom Count:10
Complexity:89.6

Purity/Quality:

99% ^*data from raw suppliers

4-Hydroxy-1-piperidineethanol 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CN(CCC1O)CCO

Technology Process of 4-Hydroxy-1-piperidineethanol

There total 1 articles about 4-Hydroxy-1-piperidineethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 540-51-2
2-bromoethanol

: 224431-84-9
4-hydroxy-1-piperidine-ethanol

Guidance literature:: With sodium carbonate; In ethanol; for 16h; Heating / reflux;

Reference yield: 62.0%

: 64-18-6
formic acid

: 1443248-40-5
1-[5-tert-butyl-2-(3-hydroxy-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea

: 224431-84-9
4-hydroxy-1-piperidine-ethanol

: 1-(5-tert-butyl-2-{3-[2-(4-hydroxy-piperidin-1-yl)-ethoxy]-phenyl}-2H-pyrazol-3-yl)-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea formate salt

Guidance literature:: 1-[5-tert-butyl-2-(3-hydroxy-phenyl)-2H-pyrazol-3-yl]-3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-urea; 4-hydroxy-1-piperidine-ethanol; With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;

formic acid; In water; acetonitrile; at 20 ℃;

Reference yield:

: 1560795-99-4
2-[2-(3,5-dimethoxyphenyl)ethyl]-5-(phenylsulfonyl)-6-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine

: 224431-84-9
4-hydroxy-1-piperidine-ethanol

: C₃₂H₃₆N₆O₅S

Guidance literature:: 4-hydroxy-1-piperidine-ethanol; With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 0.25h;

2-[2-(3,5-dimethoxyphenyl)ethyl]-5-(phenylsulfonyl)-6-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine; In tetrahydrofuran; for 16h;