2244614-14-8 Usage
Molecular structure
The compound has a complex molecular structure consisting of a quinolin-2-yl group, a piperidin-4-amine group, and a tetrahydro-2H-pyran-4-yl group.
Fluoro substituent
The presence of a fluoro substituent (F) at the 8th position of the quinolin-2-yl group may influence the compound's reactivity, stability, and lipophilicity.
Ethyl group
An ethyl group (C2H5) is attached to the 6th position of the quinolin-2-yl group, which may affect the compound's steric properties and solubility.
3-Methyl-1,2,4-oxadiazol-5-yl substituent
The presence of a 3-methyl-1,2,4-oxadiazol-5-yl group at the 3rd position of the quinolin-2-yl group may contribute to the compound's stability and potential biological activity.
Tetrahydro-2H-pyran-4-yl group
The tetrahydro-2H-pyran-4-yl group is attached to the piperidin-4-amine group, which may influence the compound's conformational flexibility and hydrogen bonding capabilities.
Potential pharmacological applications
Due to its structural features, the compound may have potential applications in the field of pharmacology, such as acting as a drug candidate or a molecular probe.
Potential biological applications
The compound's structural features may also suggest potential biological applications, such as targeting specific receptors or enzymes in biological systems.
Further research needed
To fully understand the properties and potential uses of 1-(6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)piperidin-4-amine, additional research and analysis are necessary, including studies on its chemical reactivity, stability, solubility, and biological activity.
Structural complexity
The compound's complex structure may pose challenges in terms of synthesis, purification, and characterization, requiring advanced techniques and expertise in organic chemistry and medicinal chemistry.
Potential for optimization
The compound's structure may be further modified or optimized to improve its pharmacological or biological properties, such as increasing its potency, selectivity, or bioavailability.
Check Digit Verification of cas no
The CAS Registry Mumber 2244614-14-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,2,4,4,6,1 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2244614-14:
(9*2)+(8*2)+(7*4)+(6*4)+(5*6)+(4*1)+(3*4)+(2*1)+(1*4)=138
138 % 10 = 8
So 2244614-14-8 is a valid CAS Registry Number.
2244614-14-8Relevant articles and documents
Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)
Guerrero, Miguel,Urbano, Mariangela,Kim, Eun-Kyong,Gamo, Ana M.,Riley, Sean,Abgaryan, Lusine,Leaf, Nora,Van Orden, Lori Jean,Brown, Steven J.,Xie, Jennifer Y.,Porreca, Frank,Cameron, Michael D.,Rosen, Hugh,Roberts, Edward
, p. 1761 - 1780 (2019)
κ opioid receptor (KOR) antagonists are potential pharmacotherapies for the treatment of migraine and stress-related mood disorders including depression, anxiety, and drug abuse, thus the development of novel KOR antagonists with an improved potency/selec
KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO
-
, (2018/10/19)
Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: (I) wherein X, Y, R1, R2, R4, R5 R6, R7, R8 and R11 are as defined herein.
