Welcome to LookChem.com Sign In|Join Free

CAS

  • or

228259-70-9

1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

228259-70-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 228259-70-9 Structure

  • Basic information

    1. Product Name: 1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl)
    2. Synonyms: 1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl);(1-phenylsulfonyl-4-piperidyl)amine;1-(phenylsulfonyl)piperidin-4-amine hydrochloride;1-Benzenesulfonyl-piperidin-4-ylamine;1-phenylsulfonyl-4-piperidinamine
    3. CAS NO:228259-70-9
    4. Molecular Formula: C11H16N2O2S
    5. Molecular Weight: 240.32194
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 228259-70-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl)(228259-70-9)
    11. EPA Substance Registry System: 1-(phenylsulfonyl)-4-piperidinamine(SALTDATA: HCl)(228259-70-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 228259-70-9(Hazardous Substances Data)

228259-70-9 Usage

Chemical Class

Piperidine compounds

Usage

Pharmaceutical intermediate for the synthesis of various drugs

Physical Appearance

White to off-white solid

Molecular Weight

251.77 g/mol

Melting Point

216-218°C

Preparation Method

Reaction of 1-(phenylsulfonyl)-4-piperidinol with hydrochloric acid

Safety Precautions

May cause irritation to skin, eyes, and respiratory system upon exposure; handle with care

Check Digit Verification of cas no

The CAS Registry Mumber 228259-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,8,2,5 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 228259-70:
(8*2)+(7*2)+(6*8)+(5*2)+(4*5)+(3*9)+(2*7)+(1*0)=149
149 % 10 = 9
So 228259-70-9 is a valid CAS Registry Number.

228259-70-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(benzenesulfonyl)piperidin-4-amine

1.2 Other means of identification

Product number -
Other names 1-(phenylsulfonyl)piperidin-4-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:228259-70-9 SDS

228259-70-9Downstream Products

228259-70-9Relevant articles and documents

Structure-based design of benzo[e]isoindole-1,3-dione derivatives as selective GSK-3β inhibitors to activate Wnt/β-catenin pathway

Yue, Hong,Lu, Feng,Shen, Chen,Quan, Jun-Min

, p. 21 - 27 (2015/06/16)

Deregulation of Wnt/β-catenin pathway is closely related to the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD), and glycogen synthase kinase 3β (GSK-3β), the central negative regulator of Wnt pathway, is regarded as an important target for these diseases. Here, we report a series of benzo[e]isoindole-1,3-dione derivatives as selective GSK-3β inhibitors by rational-design and synthesis, which show high selectivity against GSK-3β over Cyclin-dependent kinase 2 (CDK2), and significantly activate the cellular Wnt/β-catenin pathway. The structure-activity relationship of these GSK-3β inhibitors was also explored by in silico molecular docking.

DIPEPTIDYL PEPTIDASE IV INHIBITOR

-

Page/Page column 79, (2010/11/29)

A compound represented by general formula (I):A-B-D whereinA represents a substituted or unsubstituted 1-pyrrolidinyl group, a substituted or unsubstituted 3-thiazolidinyl group, a substituted or unsubstituted 1-oxo-3-thiazolidinyl group, or the like;B r

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 228259-70-9