234094-01-0Relevant articles and documents
A practical manufacturing synthesis of 1-(R)-hydroxymethyl-DTPA: An important intermediate in the synthesis of MRI contrast agents
Amedio Jr., John C.,Bernard, Paul J.,Fountain, Mark,Van Wagenen Jr., Gerritt
, p. 2377 - 2391 (1999)
An efficient synthesis of alcohol 2 is described from L-Serine (OMe) in four synthetic steps. The process uses readily available reagents and is suitable for manufacturing.
PROCESS FOR MANUFACTURE OF GADOFOSVESET TRISODIUM MONOHYDRATE
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Page/Page column 15; 16, (2014/10/15)
This application relates to a process for making a pharmaceutically acceptable formulation of gadofosveset trisodium monohydrate, wherein the process uses no more than one chromatographic purification for removal of impurities.