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Methyl 4-{[(4-methoxyphenyl)methyl]amino}-3-nitrobenzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

234751-03-2

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234751-03-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 234751-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,4,7,5 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 234751-03:
(8*2)+(7*3)+(6*4)+(5*7)+(4*5)+(3*1)+(2*0)+(1*3)=122
122 % 10 = 2
So 234751-03-2 is a valid CAS Registry Number.

234751-03-2Relevant articles and documents

Synthesis and biological evaluation of quinoxaline derivatives as tubulin polymerization inhibitors that elevate intracellular ROS and triggers apoptosis via mitochondrial pathway

Qi, Jianguo,Huang, Jing,Zhou, Xiaomin,Luo, Wen,Xie, Jiaxin,Niu, Linqiang,Yan, Zhijie,Luo, Yang,Men, Yuhui,Chen, Yanan,Zhang, Yahong,Wang, Jianhong

, p. 617 - 627 (2019/01/18)

A series of novel quinoxaline derivatives were synthesized and evaluated for their antiproliferative activity in three human cancer cell lines. Compound 12 exhibited the most potent antiproliferative activity with IC50 in the range of 0.19–0.51

3D-Printed Polypropylene Continuous-Flow Column Reactors: Exploration of Reactor Utility in SNAr Reactions and the Synthesis of Bicyclic and Tetracyclic Heterocycles

Rao, Zenobia X.,Patel, Bhaven,Monaco, Alessandra,Cao, Zi Jing,Barniol-Xicota, Marta,Pichon, Enora,Ladlow, Mark,Hilton, Stephen T.

supporting information, p. 6499 - 6504 (2017/09/25)

3D printing has the potential to transform the way in which chemical reactions are carried out due to its low-cost, ease-of-use as a technology and its capacity to expedite the development of iteratively enhanced prototypes. In this present study, we developed a novel, low-cost polypropylene (PP) column reactor that was incorporated into an existing continuous-flow reactor for the synthesis of heterocycles. The utility and solvent resistance of the printed devices were explored in SNAr reactions to produce substituted aniline derivatives and in the synthesis of bicyclic and tetracyclic heterocycles. Using this approach, a range of heterocyclic compounds was synthesised including the core structure of the natural product (±)-γ-lycorane and structurally complex compounds based on the tetracyclic core of the erythrina alkaloids.

Copper catalyzed aerobic oxidative cyclization and ketonization: One pot synthesis of benzoimidazo[1,2-: A] imidazolones

Selvaraju, Manikandan,Ye, Tzuen-Yang,Li, Chia-Hsin,Ho, Pei-Heng,Sun, Chung-Ming

supporting information, p. 6621 - 6624 (2016/06/01)

A highly efficient synthesis of benzoimidazo[1,2-a]imidazolone through a novel oxidative 5-exo-dig cyclization-ketonization cascade of 2-aminobenzimidazole, aldehyde and terminal alkyne has been explored under aerobic conditions. The reaction proceeds thr

QUINOXALINE COMPOUNDS AND USES THEREOF

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Paragraph 00265, (2015/11/09)

This invention provides compounds of formula I and subsets thereof: wherein T, J, R, R4, Rq, o, RA, and RB and subsets thereof are as described in the specification. The compounds are inhibitors of NAMPT and are thus useful for treating cancer, inflammatory conditions, or T-cell mediated autoimmune disease.

A concise synthesis of 2-(2-aminothiophene)-benzimidazoles by one-pot multicomponent reaction

Chen, Li-Hsun,Chuang, Ying-Sheng,Narhe, Bharat D.,Sun, Chung-Ming

, p. 13934 - 13943 (2013/08/23)

A one-pot synthesis of 2-aminothiophene linked benzimidazoles was achieved by utilizing 2-cyanomethyl benzimidazoles in a modified Gewald multicomponent reaction. The synthetic strategy of the reaction involved treatment of 2-(cyanomethyl)-benzimdazole wi

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

-

, (2012/07/27)

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

A facile IL-DMSO assisted synthesis of 5-, 6-, and 7-membered benzo-annelated cyclic guanidines

Verma, Amit,Giridhar, Rajani,Modh, Pratik,Yadav, Mange Ram

scheme or table, p. 2954 - 2958 (2012/07/28)

A new and facile IL-DMSO assisted method has been developed for the synthesis of biologically important cyclic guanidines like 2-aminobenzimidazole, 2-imino-4-quinazolinone, and 2-imino-5-benzotriazepinones at ambient temperatures. The desired products could be obtained by microwave irradiation32 also, but at elevated temperatures. A plausible mechanism for catalysis has been proposed.

Liquid phase synthesis of arylamines and its application to the benzimidazolone via nucleophilic aryl substitution

Pan, Pi-Chi,Sun, Chung-Ming

, p. 1537 - 1540 (2007/10/03)

A method for soluble, inexpensive polymer-supported synthesis of aryl amines and benzimidazolone on the basis of nucleophilic aryl substitution (S(N)Ar) is described. This method involves a direct coupling reaction between resin bound aryl fluoride and amines at ambient temperature. The products are isolated in quantitative yields and excellent purity by simple precipitation and washing. This liquid phase method proves to be a useful tool for constructing combinatorial arylamine and benzimidazolone libraries.

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